The level of products of lipid peroxidation in the blood of piglets at the action feed additive “Sylimevit”
Intensive pig breeding has been reported in the literature to suggest that early weaning of piglets from sows is an extreme stimulus that reduces the protective and adaptive responses of piglets. That is why the aim of the study was to study the effect of the feed additive “Sylimevit” on the level of lipid peroxidation products of piglets after weaning. Two groups of piglets were formed – control and experimental in the amount of 10 individuals in each group, selected on the principle of analogs – age, breed and body weight. During the weaning period, the piglets were kept under the sow in special machines, had constant access to the mother, and from the age of 5 days – free access to concentrated feed. While feeding of animals was carried out in accordance with the norms for a given age of pigs. Prior to the study, a clinical and physiological examination of the piglets was performed. Their general condition and activity when eating food were taken into account. On the 28th day of life, the piglets were weaned from the sow and regrouped from different nests in order to be further maintained during the period of fattening and rearing with a change in the structure of the diet, which served as technological stress for the animals. From the age of 5 days, piglets of all groups were fed pre-starter feed. Piglets of the experimental group, from 21 to 40 days of age, were additionally fed the feed supplement “Sylimevit” at a dose of 100 mg/kg body weight per day. The technological stress of weaning piglets from sows is accompanied by a gradual probable intensification of lipid peroxidation processes. Feeding Sylimevit feed to piglets after weaning helped to reduce the content of intermediate and final products of lipid peroxidation: lipid hydroperoxides – by 52 % (P < 0.001) and TBA-active products – by 22.5 % (P < 0.01). Thus, feeding the piglets of the experimental group of the feed additive “Sylimevit” helped to suppress the processes of lipid peroxidation in animals. Thus, the results of the use of feed additive “Sylimevit” in weaned piglets showed a pronounced antioxidant effect. The components of the feed additive directly interacted with reactive oxygen species and free radicals, preventing the development of oxidative stress.
Ariza-Nieto, C., Bandrick, M., Baidoo, S. K., Molitor, T. W., & Hathaway, M. R. (2011). Effect of dietary sup-plementation of oregano essential oils to sows on co-lostrum and milk composi-tion, growth pattern and immune status of suckling pigs. Journal of Animal Science, 89(4), 1079–1089. doi: 10.2527/jas.2010-3514.
Bulter, J., Sinkora, M., & Wertz, N. (2006). Development of the neonatal B and T cell repertoire in swine: impli-cations for com-parative and veterinary immunology. Veterinary Research, 37(3), 417–441. doi: 10.1051/vetres:2006009.
Czech, A., Smolczyk, A., & Ognik, K. (2018). Effect of dietary supplementation with Yarrowia lipolytica or Saccharomyces cerevisiae yeast and probiotic addi-tives on haematological parameters and the gut mi-crobiota in piglets. Research in Veterinary Science, 119, 221–227. doi: 10.1016/j.rvsc.2018.06.007.
De Lange, C., Pluske, J. R., Gong, J., & Nyachoti, C. M. (2010). Strategic use of feed ingredients and feed ad-ditives to stimulate gut health and development in young pigs. Livestock Science, 134(1-3), 124–134. doi: 10.1016/j.livsci.2010.06.117.
Frankic, T., Levart, A., & Salobir, J. (2010). The effect of vitamin E and plant extract mixture composed of carvacrol, cinnamalde-hyde and capsaicin on oxida-tive stress induced by high PUFA load in young pigs. Animal, 4(4), 572–578. doi: 10.1017/S1751731109991339.
Gutyj, B., Leskiv, K., Shcherbatyy, A., Pritsak, V., Fedo-rovych, V., Fedorovych, O., Rusyn, V., & Kolomiiets, I. (2017). The influence of Metisevit on biochemical and morphological indicators of blood of piglets under nitrate loading. Regulatory Mechanisms in Biosys-tems, 8(3), 427–432. doi: 10.15421/021766.
Gutyj, B., Martyshchuk, T., Bushueva, I., Semeniv, B., Parchenko, V., Kaplaushenko, A., Magrelo, N., Hirkovyy, A., Musiy, L., & Murska, S. (2017). Mor-phological and biochemical indicators of blood of rats poisoned by carbon tetrachloride and subject to ac-tion of liposomal preparation. Regulatory Mecha-nisms in Biosystems, 8(2), 304–309. doi: 10.15421/021748.
Gutyj, B., Khariv, I., Khalak, V., Khariv, M., Vasiv, R., Leskiv, Kh., Martyshuk, T., & Guta, Z. (2021). The ef-fect of liposomal drug “Butaintervit” on the activity of the t-system of cellular immunity of rats under oxi-dative stress. Colloquium-journal, 22(109), 14–18. doi: 10.24412/2520-6990-2021-22109-14-18.
Han, C., Dai,Y., Liu, B. Wang, L., Wang, J., & Zhang, J. (2019). Diversity analysis of intestinal microflora be-tween healthy and diarrheal neonatal piglets from the same litter in different re-gions. Anaerobe, 55, 136–141. doi: 10.1016/j.anaerobe.2018.12.001.
Hedemann, M. S., & Jensen, B. B. (2004). Variations in enzyme activity in stomach and pancreatic tissue and digesta in piglets around weaning. Archives of Animal Nutrition, 58(1), 47–59. doi: 10.1080/00039420310001656677.
Heo, J. M., Opapeju, F. O., & Kim, J. C. (2012). Gastroin-testinal health and function in weaned pigs: a review of feeding strate-gies to control post-weaning diar-rhoea without using in-feed an-timicrobial com-pounds. Journal of Animal Physiology and Ani-mal Nutrition, 97(2), 207–237. doi: 10.1111/j.1439-0396.2012.01284.x.
Ivankiv, M., Kachmar, N., Mazurak, O., & Martyshuk, T. (2019). Hepatic protein synthesis and morphological parameters in blood of rats under oxidative stress and action of feed additive “Bu-taselmevit-plus”. Ukraini-an Journal of Ecology, 9(4), 628–633. URL: https://www.ujecology.com/abstract/hepatic-protein-synthesis-and-morphological-parameters-in-blood-of-rats-under-oxidative-stress-and-action-of-feed-additi-44975.html.
Jacela, J. Y., DeRouchey, J. M., & Tokach, M. D. (2010). Feed additives for swine: Fact sheets – prebiotics and probiotics, and phytogenics. Kansas Agricultural Ex-periment Station Research Reports, 18(3), 132–136. doi: 10.4148/2378-5977.7067.
Khalak, V., & Gutyj, B. (2020). Physicochemical proper-ties and chemical composition of muscle tissue of young pigs of large white breed and their correlation with some serum enzymes. Ukrainian Journal of Vet-erinary and Agricultural Sciences, 3(3), 34–38. doi: 10.32718/ujvas3-3.07.
Khalak, V., Dudchak, I., Gutyj, B., Stadnytska, O., Vakulik, V., Pundiak, T., Zmiia, M., Slepokura, O., Bordun, O., Smyslov, S. (2021). Some biochemical in-dicators of serum, fattening, and meat quality of young pigs of different classes of distribution accord-ing to the Sazer-Fredin index. Ukrainian Journal of Ecology, 11(7), 6–13. doi: 10.15421/2021_236
Khalak, V., Gutyj, B., Stadnytska, O., Shuvar, I., Balkov-skyi, V., Korpita, H., Shuvar, A., Bordun, О. (2021). Breeding value and productivity of sows of the Large White breed. Ukrainian Journal of Ecology, 11(1), 319–324. doi: 10.15421/2021_48.
Khalak, V., Gutyj, B., Bordun, O., Ilchenko, M., & Horchanok, A. (2020). Effect of blood serum en-zymes on meat qualities of piglet productivity. Ukrainian Journal of Ecology, 10(1), 158–161. doi: 10.15421/2020_25.
Khalak, V., Gutyj, B., Bordun, О., Horchanok, A., Ilchen-ko, M., Smyslov, S., Kuzmenko, O., & Lytvyshchen-ko, L. (2020). De-velopment and reproductive quali-ties of sows of different breeds: innovative and tradi-tional methods of assessment. Ukrainian Journal of Ecology, 10(2), 356–360. doi: 10.15421/2020_109.
Khariv, M., Gutyj, B., Butsyak, V., & Khariv, I. (2016). Hematological indices of rat organisms under condi-tions of oxidative stress and liposomal preparation ac-tion. Biological Bulletin of Bogdan Chmelnitskiy Meli-topol State Pedagogical University, 6(1), 276–289. doi: 10.15421/201615.
Khariv, M., Gutyj, B., Ohorodnyk, N., Vishchur, O., Khariv, I., Solovodzinska, I., Mudrak, D., Grymak, C., & Bodnar, P. (2017). Activity of the T- and B-system of the cell immunity of animals under conditions of oxidation stress and effects of the liposomal drug. Ukrainian Journal of Ecology, 7(4), 536–541. doi: 10.15421/2017_157.
Kramarenko, S. S., Lugovoy, S. I., Kharzinova, V. R., Lykhach, V., Kramarenko, A. S., & Lykhach, A. V. (2018). Genetic diversity of Ukrainian local pig breeds based on microsatellite markers. Regulatory Mecha-nisms in Biosystems, 9(2), 177–182. doi: 10.15421/021826.
Kramarenko, S., Lugovoy, S., Lykhach, A., Kramarenko, A., & Lykhach, V. (2018). A comparative study of the reproductive traits and clustering analysis among dif-ferent pig breeds. Scien-tific Messenger of LNU of Veterinary Medicine and Biotechnol-ogies. Series: Ag-ricultural Sciences, 20(84), 21–26. doi: 10.15421/nvlvet8404.
Kramarenko, S., Lugovoy, S., Lykhach, A., Kramarenko, A., Lykhach, V., & Slobodianyk, A. (2019). Effect of genetic and non-genetic factors on the reproduction traits in Ukrainian Meat sows. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Se-ries: Agricultural Sciences, 21(90), 3–8. doi: 10.32718/nvlvet-a9001.
Lavryshyn, Y. Y., Varkholyak, I. S., Martyschuk, T. V., Guta, Z. А., Ivankiv, L. B., Paladischuk, О. R., Murska, S. D., Gutyj, B. V., & Gufriy, D. F. (2016). The biological significance of the antioxidant defense system of animals body. Scientific Messenger LNUVMBT named after S.Z. Gzhytskyj, 18(2(66)), 100–111. doi: 10.15421/nvlvet6622.
Martyshuk, T.V., Gutyj, B.V., & Vishchur, O.I. (2016). Level of lipid peroxidation products in the blood of rats under the influence of oxidative stress and under the action of liposomal preparation of ‘‘Bu-taselmevit’’. Biological Bulletin of Bogdan Chmelnitskiy Melitopol State Pedagogical University, 6(2), 22–27. doi: 10.15421/201631.
Martyshuk, T. V., Gutyj, B. V., Vishchur, O. I., & Todori-uk, V. B. (2019). Biochemical indices of piglets blood under the action of feed additive “Butaselmevit-plus”. Ukrainian Journal of Veterinary and Agricultural Sci-ences, 2(2), 27–30. doi: 10.32718/ujvas2-2.06.
Martyshuk T. V., Gutyj B. V., Vishchur O. I. (2019). Mor-phological and biochemical indices of piglets' blood by the action of feed additive “Butaselmevit-plus”. The Animal biology, 21(4), 65–70. doi: 10.15407/animbiol21.04.065.
Martyshuk, T. V., Gutyj, B. V., Zhelavskyi, M. M., Midyk. S. V., Fedorchenko, A. M., Todoriuk, V. B., Nahirniak, T. B., Kisera, Ya. V., Sus, H. V., Chemerys, V. A., Lev-kivska, N. D., & Iglitskej, I. I. (2020). Effect of Bu-taselmevit-Plus on the immune system of piglets dur-ing and after weaning. Ukrainian Journal of Ecology, 10(2), 347–352. doi: 10.15421/2020_106
Martyshuk, T. V., Gutyj, B. V., Leskiv, Kh. Ya., Se-maniuk, N. V., & Shnaider, V. L. (2021). The effect of the liposomal drug “butaselmevit” on the enzymatic and non-enzymatic part of the glutatoin system of the blood of rats under oxidative stress. Colloquium-journal, 12(99), 16–19.
Martyshuk, T., Gutyj, B., & Khalak, V. (2021). System of antioxidant protection of the body of piglets under the action of feed additive “Butaselmevit-plus”. Ukraini-an Journal of Veterinary and Agricultural Sciences, 4(2), 38-43. doi: 10.32718/ujvas4-2.07.
Martyshuk, T. V., & Hutyi, B. V. (2021). Imunofiziolohichnyi stan ta antyoksydantnyi potentsial orhanizmu porosiat za umov oksydatsiinoho stresu ta dii koryhuiuchykh chynnykiv: monohrafiia. Lviv: SPOLOM (in Ukraini-an).
Ostapyuk, A.Y., Holubieva, T.A., Gutyj, B.V., & Slobodi-an, S.O. (2021). The effect of sylimevit, metifen, and milk thistle on the intensity of the processes of peroxi-dation of lipids in the body of laying hens in experi-mental chronic cadmium toxicosis. Ukrainian Journal of Ecology, 11(4), 57–63. doi: 10.15421/2021_199.
Sobolev, А., Gutyj, B., Grynevych, N., Bilkevych, V., & Mashkin, Y. (2017). Enrichment of meat products with selenium by its introduction to mixed feed com-pounds for birds. Regulatory Mechanisms in Biosys-tems, 8(3), 417–422. doi: 10.15421/021764.
Stojanovskyj, V., & Ogrodnyk, M. (2016). Function of intestinal immune barrier of piglets under technologi-cal stress. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sci-ences, 18(3(71), 112–116. doi: 10.15421/nvlvet7126.
Studenok, A. A., Shnurenko, E. O., Karpovskyi, V. I., Trokoz, V. O. & Gutyj, B. V. (2021). Indicators of pro-tein metabolism and intensity of lipid peroxide oxida-tion in chickens with different vegetative status. Scien-tific Messenger of Lviv National University of Veteri-nary Medicine and Biotechnologies. Series: Veterinary sciences, 23(102), 110–118. doi: 10.32718/nvlvet10217.
Varkholiak, I.S., Gutyj, B.V., Leskiv, Kh.Ya., Kushnir, V.I., Hariv, I. I., Martyshuk, T. V., & Guta Z. A. (2021). The effect of bendamine on antioxidant pro-tection of rats' myocardium in doxorubicin intoxication. Colloquium-journal, 7(94), 18–21. doi: 10.24412/2520-6990-2021-794-18-21.
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