Influence of mercury on the human and animal organism
In the list of environmental pollutants, mercury is one of the first places. It is mercury, its inorganic and especially organic compounds belong to extremely toxic substances of the first class of danger.Mercury has been known since ancient times, it is mentioned in the writings of Aristotle, Theophrastus, Pliny the Elder, Vitruvius and other ancient scholars. The Latin name for this metal is “Hydrargium”, given to mercury by Greek physician Dioscorides (1st century B.C.), means in translation “silver water”. The most important and ancient in Ukraine is the Mykytiv mercury deposit, which was opened in 1879. and operated since 1885. Production of mercury until 1914 was 300–400 t/year (most of it was exported). After the revolution and the war it was slowly recovered (127 tons in 1926), in 1935–1940 it is annually brought to about 300 tons. After the Second World War, the Mykytiv deposit was built. Discovered in it reserves (up to a depth of 300 m) were evaluated in 6.000 tons in 1927, after deep drilling was introduced in the 1960s. they have increased slightly. In the world economy, mercury is widely used in the electrical engineering and instrument industry, laboratory and medical practice, in the production of chlorine/alkali, in agriculture (included in fertilizers), in small-scale mining of gold and silver and other fields. No other chemical element belonging to the first class of danger has such wide use in production processes, products, substances and such multivariate penetration into the organism (with air, food, water, through the skin) as mercury and its compounds. The main source of mercury poisoning is mercury vapor and dust of mercury compounds. The toxicity of metallic mercury is due to the fact that while inhaling its vapors more than 80 % of the mercury is absorbed by the brain, kidneys and other internal organs, leading to he devastating consequences primarily on the central nervous system and kidneys. Mercury semi withdrawal period from humans is from 35 to 96 days. The average semi withdrawal period from the blood is 65 days, from hair 72 days, in total from the organism - 76 days. A longer semi withdrawal period of mercury from the brain than from other organs has been recorded in experimental animal searches. In humans, high levels of mercury in brain tissue were detected 10 years after it ceased contact with a toxic substance. Mercury poisoning can be acute or chronic. In everyday life, most often find the second option.
Chaikovskyi, B. P., Hrymaliuk, B. T., Yaroshovych, I. H., Shalko, A. V., & Pavlyk, N. I. (2014). Hostri otruiennia rtuttiu. Silskyi hospodar. Lviv, 9–10, 32–33 (in Ukrainian).
Chaikovskyi, B. P., Hrymaliuk, B. T., Yaroshovych, I. H., Shalko, A. V., & Pavlyk, N. I. (2014). Khronichne otruiennia paramy rtuti. Silskyi hospodar. Lviv, 11–12, 28–30 (in Ukrainian).
Davidson, P. W., Myers, G. J., & Weiss, B. (2004). Mercury exposure and child development outcomes. Pediatrics, 113, 1023–1029. https://www.ncbi.nlm. nih.gov/pubmed/15060195.
DSNiP “Hihiienichna klasyfikatsiia pratsi za pokaznykamy shkidlyvosti i nebezpechnosti faktoriv vyrobnychoho sere-dovyshcha, vazhkosti ta napruzhenosti trudovoho protsesu” zatverdzhenyi Nakazom MOZ Ukrainy vid 08.04.2014r. № 248 (in Ukrainian).
DSPiN 18.104.22.1688-99 “Pravyla zboru, zberihannia i vydalennia vidkhodiv likuvalno-profilaktychnykh ustanov” (in Ukrainian).
Efimova, N. V. (2001). Rtut': opasnost' real'naja i mnimaja. Irkuts'k (in Russian).
Geier, D. A., King, P. G., Hooker, B. S. et al. (2015). Thimerosal: clinical, epidemiologic and biochemical studies. Clin. Chim. Acta., 444(15), 212–220. doi: 10.1016/j.cca.2015.02.030.
Joshi, D., Mittal, D. K., Shukla, S., & Srivastav, A. K. (2012). Therapeutic potential of N-acetyl cysteine with antioxidants (Zn and Se) supplementation against dimethylmercury toxicity in male albino rats. Exp. Toxicol. Pathol., 64(1–2), 103–108. doi: 10.1016/j.etp.2010.07.001.
Khabarov, A. A., Bulatnikova, V. A., & Konchinova, O. F. (1997). Biolohichna rol khimichnykh elementov. KHMU Kursk (in Ukrainian).
Moeseenko, V. G., Radomskaja, V. I., Bejd, S. M., & Hajli, Je. (2005). Toksichnost' rtuti. Medikalveritas, 535–542 (in Russian).
Moiseienko, V. T., Radomskyi, S. M., & Radomskaia, V. Y. (2004). Intoksikacija chelovecheskogo organizma metallicheskoj rtut'ju. Vestnik DVORAN, 3, 100–110 (in Russian).
Nelson, K. B., & Bauman, M. L. (2003). Thimerosal and autism? Pediatrics, 111(3), 674–679. doi: 10.1542/peds.111.3.674.
NPAOP 73.1-1.11-12. Pravyla okhorony pratsi pid chas roboty v khimichnykh laboratoriiakh (in Ukrainian).
Opeida, Y., & Shvaika, O. (2008). Hlosarii terminiv z khimii. In-t fizyko-orhanichnoi khimii ta vuhlekhimii im. L. M. Lytvynenka NAN Ukrainy, Donetskyi natsionalnyi universytet. Donetsk: “Veber” (in Ukrain-ian).
Pirrone, N. Costa, P., Pacyna, J. M., & Ferrara, R. (2001). Atmospheric Mercury Emissions from Anthropogenic and Natural Sources in the Mediterranean Region. Atmospheric Environment, 35, 2997–3006.
Prymirna instruktsiia z okhorony pratsi pry robotakh iz pryladamy z rtutnym napovnenniam, zatverdzhena naka-zom Ministerstva promyslovoi polityky Ukrainy vid 19.08.2005 № 311 (in Ukrainian).
Rice, K. M., Walker, E. M., Wu, M. et al. (2014). Environmental mercury and its toxic effects. J. Prev. Med. Public Health., 47(2), 74–83. doi: 10.3961/jpmph.2014.47.2.74.
Tan, M., & Parian, J. E. (2000). Route of decomposition of thiomersal (thimerosal). lnt. J. Pharm., 208(1–2), 23–34. doi: 10.1016/S0378-5173(00)00514-7.
Trakhtenberh, I. M., Krasnokutska, L. M., & Lubianova, I. P. (2016). Rtut ta yii nebezpeka – problema davnia i nova. Ukrayinskyi zhurnal suchasnykh problem toksykolohii, 1(73) (in Ukrainian).
Zaharov, L. N. (1991). Tehnika bezopasnosti v himicheskih laboratorijah: Himija (in Russian).
Abstract views: 61 PDF Downloads: 129