Analysis of innovative technologies of hydrogels from uronate polysaccharides and biodegradable films on their basis

Keywords: uronate polysaccharides, alginate, pectin, xanthan, hyaluronic acid, hydrogels, immobilization, “cross-copolymerization”


The article is devoted to the analysis of the state and dynamics of scientific developments in the field of creating products for life and health, based on hydrogels from uronate polysaccharides (HUP). The article is reflected the results of the global scientific research monitoring and their changes in the field of technologies for the creation and use of HUP. The results of a retrospective analysis of existing technologies based on poorly studied in the field of food technologies uronic acids, as glucuronic, idouronic, hyaluronic were presented. The study showed, that nowadays the industry of products with their content is acquiring market traits, although it has insufficient scientific substantiation. Development segments with widely used uronate polysaccharides – pectins and alginates – according to the types of hydrogels (swollen hydrogel, cross-linked hydrogel, xerogel) were developed. The article presents examples and identified the required properties of substances intended for immobilization or encapsulation in the hydrogel matrix of uronate polysaccharides. The basic principles of uronate polysaccharides crosslinking chains in the hydrogel phase are determined. Possible methods of biologically active substances (BAS) retention in the matrix of uronate polysaccharides to reduce the risk of premature oxidation, destruction, decomposition, decomposition, evaporation were described. The search for information allowed us to identify key technological areas for the development of scientific research on the creation and use of HUP to improve people's lives and health. The archives of the world's leading publications in the field of food chemistry, biotechnology, food engineering, chemistry of new materials, food polymers and hydrocolloids were analyzed. The authors used in their work the resources of the Science Direct search system, which made it possible to determine the most promising and modern lines of development of HUP technologies and products based on them. The analysis of technologies has shown that existing innovative technologies are formed on “basic” technologies for producing solutions of high-molecular compounds under various conditions. Active modernization is carried out in the direction of creating products with immobilized biologically active substances, as well as in attempts to compose a composition with other polysaccharides and/or peptide components. The article notes that existing technologies allow developing other technologies with the help of which it is possible to expand the field of HUP application.


Bilanovic, D., Starosvetsky, J., & Armon, R.H. (2016). Preparation of biodegradable xanthan–glycerol hydrogel, foam, film, aerogel and xerogel at room temperature. Carbohydrate Polymers, 148, 243–250. doi: 10.1016/j.carbpol.2016.04.058.

Bušić, A., Belščak-Cvitanović, A., & Cebin, A.V. (2018). Structuring new alginate network aimed for delivery of dandelion (Taraxacum officinale L.) polyphenols using ionic gelation and new filler materials. Food Re-search International, 111, 244–255. doi: 10.1016/j.foodres.2018.05.034.

Enas, M.A. (2015). Hydrogel: Preparation, characteriza-tion, and applications: A review Journal of Advanced Research, 6, 105–121 doi: 10.1016/j.jare.2013.07.006.

Gomez, L., Ramırez, H.L., Villalonga, M.L., & Hernan-dez, J. (2006). Immobilization of chitosan-modified invertase on alginate-coated chitin support via poly-electrolyte complex formation. Enzyme and Microbial Technology, 38, 22–27. doi: 10.1016/j.enzmictec.2004.10.008.

Karača, S., Trifković, K., Bušić, A., & Dordević, V. (2019). The functional potential of immortelle (Helichrysum italicum) based edible films reinforced with proteins and hydrogel particles. Food Science and Technology, 99, 387–395. doi: 10.1016/j.lwt.2018.09.039.

Kokkarachedu, V., Gownolla, M.R., & Tippabattini, J. (2017). A mini review on hydrogels classification and recent developments in miscellaneous applications. Materials Science and Engineering, 79, 958–971. doi: 10.1016/j.msec.2017.05.096.

Kondratiuk, N.V., & Pyvovarov, Ye.P. (2017). Kharchovi uronatni hidroheli yak osnova stratehii zdorovoho kharchuvannia u zakladakh restorannoho hospodarstva. Aktualni problemy rozvytku restorannoho, hotelnoho ta turystychnoho biznesu v umovakh svitovoi intehratsii: doslidzhennia ta perspektyvy (in Ukrainian).

Kondratiuk, N.V., Mulyk, R.Y., & Polyvanov, Y.A. (2017). New prospects for making food gels based on uronic polysaccharides. III International Scientific and Practical-Conference “Modern Methodology of Science and Education”, 6(22), 1, 48–50.

Kondratiuk, N.V., Stepanova, T.M., & Toloshnyi, D.V. (2018). Heli kharchovi plivkoutvoriuiuchi na osnovi uronatnykh polisakharydiv u vyrobnytstvi sumishei dlia iniektuvannia miasoproduktiv. Vcheni zapysky TNU imeni V.I. Vernadskoho. Seriia: tekhnichni nauky, 29(68), 20–25 (in Ukrainian).

Kondratiuk, N.V., Stepanova, Т.М., & Burak, V.G. (2018). The food envelop forming coatings using on the basis of uronate polysaccharides in manufacture of chocolate products with protein hydrolyzate. The development of technical sciences: problems and solutions: Conference Proceedings, April 27–28, Brno: Baltija Publishing, 53–56.

Laís, B.N., Juliano, E.O., Francys, K.V., & Moreira, J.M. (2018). Rheological and thermo-mechanical evalua-tion of bio-based chitosan/pectin blends with tunable ionic cross-linking. International Journal of

Biological Macromolecules, 118, 1817–1823. doi: 10.1016/j.ijbiomac.2018.07.027.

Liu, Q., Jing, Y., Han, C., Zhang, H., & Tian, Y., (2019). Encapsulation of curcumin in zein/ caseinate/sodium alginate nanoparticles with improved physicochemical and controlled release properties. Food Hydrocolloids, 93, 432–442. doi: 10.1016/j.foodhyd.2019.02.003.

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Kondratiuk, N., Stepanova, T., & Chernushenko, O. (2019). Analysis of innovative technologies of hydrogels from uronate polysaccharides and biodegradable films on their basis. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Food Technologies, 21(91), 100-103.