Impact of antioxidants on enzym activities of glutatione system of bulls bodies antioxidant defense under acute nitrate and nitrite toxicity


  • V. Huberuk
  • B. Gutyj
  • D. Gufriy
  • V. Binkevych
  • I. Hariv
  • O. Binkevych
  • R. Salata
Keywords: nitrates, bulls, antioxidants, toxicology, antioxidant system

Abstract

The article presented the results of studies of the effect of sodium nitrate on indexes of glutatione system of antioxidant defense system in young cattle, such as the activity of glutathionereductase, glutathioneperoxidase and glucose-6-phosphate dehydrogenase. It was founded that feeding bulls with the toxicants at a dose 0,45 NО3¯ / kg enzyme activity in the blood of experimental animals throughout the experiment decreased. After using the nitrate load of young cattle it was used drugs Ursovit-ADES and sodium selenite. It was founded stimulatory effects on activity of glutathione system of antioxidant defense. Specifically,it was founded significant activity increase of glutathionereductase, glutathioneperoxidase and glucose-6-phosphatedehydrogenase. in the blood of young cattle, which were conducted with nitrate loading.

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Published
2017-03-06
How to Cite
Huberuk, V., Gutyj, B., Gufriy, D., Binkevych, V., Hariv, I., Binkevych, O., & Salata, R. (2017). Impact of antioxidants on enzym activities of glutatione system of bulls bodies antioxidant defense under acute nitrate and nitrite toxicity. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sciences, 19(77), 220-224. Retrieved from https://nvlvet.com.ua/index.php/journal/article/view/1212

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