Efficiency of treatment of postpartum endometritis of cows with aerosol preparation «Tsefhen»


  • O.A. Katsaraba
  • O.J. Dmytriv
  • Ye.Ye. Kostyshyn
  • R.M. Ivashkiv
  • S.Yo. Kava
  • R.N. Sachuk
Keywords: obstetric pathology, endometritis, postnatal intrauterine infections, etiotropic therapy, «Hysterosol», «Tsefhen», service period

Abstract

Today, the main method of treatment and prevention of intrauterine diseases remains local etiotropic therapy, which is based on the introduction of antimicrobial and anti-inflammatory drugs directly into the uterus. Unfortunately, the standard schemes for the use of modern medicines do not always provide a sufficient therapeutic effect. Therefore, for the treatment of postnatal infections in animals, it is better to use high-intensity antibiotics in the form of aerosols, for example, cephalosporins, which are increasingly used in the treatment of postnatal pathology in animals. Actually therefore we proposed for the prevention and treatment of obstetric pathology in cows after calving a highly active drug in the form of aerosols «Tsefhen». To study the therapeutic efficacy of «Tsefhen», two experimental groups were formed («Tsefhen» was administered in the first group, «Hysterosol» was administered in the second group), and control (only uterine massage) was performed on 6 animals, each of which was diagnosed with purulent catarrhal metritis. Intrauterine use of the drug «Tsefhen» during 3 days with purulent-catarrhal metritis ensured the recovery of 6 cows for 5 days, and a five-time use of «Hysterosol» contributed to the recovery of 5 diseased animals for 8 days. In the control group of cows, recovery was observed in 4 cows for 14 days. The effectiveness of the used drug is indicated by the service period and the index of insemination, which in the first experimental group was 58.7 mg in the index of insemination of 1.0 units, in the second experiment it was 70.0 days for the insemination index 1.2, compared with the control animals where the service period was 113.0 days at an index of 1.6. Based on this data, we recommend using aerosol «Tsefhen» in the treatment and prophylaxis of obstetric pathology.

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References

Dmytriyev, I.M., Zhygalyuk, S.V., Luk'yanyk, I.M., Kaczaraba, O.A. (2015). «Cefgen» - suchasnyj pinoutvoryuyuchyj aerozolnyj preparat dlya profilakty`ky` ta likuvannya pislyarodovyx vnutrishn`omatkovy`x infekcij u produktyvnyx tvaryn. Materialy shhorichnoyi naukovo-praktychnoyi konferenciyi molodyx vchenyx «Aktualni problemy veterynarnoyi biotexnologiyi ta infekcijnoyi patologiyi tvaryn». Kyyiv, 19–21 (in Ukrainian).

Dmitriev, I.N., Luk'janik, I.N., Kacaraba, O.A., Stravs'kij, Ja.S. (2015). Razrabotka sostava i opredelenie jeffektivnosti novogo aerozol'nogo preparata «Cefgen» pri zaderzhanii posleda u korov. Materialy ІV mezhdunarodnoj konferencii «Innovacionnye razrabotki molodyh uchenyh – razvitiju agropromyshlennogo kompleksa»: Sbornik nauchnyh trudov. FGBNU VNIIOK, Stavropol'. 1(8), 407–409 (in Russian).

Dmytriyev, I.M., Lazutkina, A.O., Kaczaraba, O.A., Zhygalyuk, S.V., Stravskyj, Ya.S., Luk'yanyk, I.M., Dmytriv, O.Ya., Kava, S.J. (2015). Aerozolnyj preparat dlya profilaktyky ta likuvannya pislyarodovyx vnutrishnomatkovyx infekcij u tvaryn «Cefgen». Pat. Ukrayiny na korysnu model № 105086, Byul. № 5 (in Ukrainian).

Bodnar, O.O., Kernychnyj, S.P. (2007). Ixtioloterapiya pry likuvannya endometrytu. Zdorovya tvaryn i liky. 12, 14–15. (in Ukrainian).

Williams, E.J., Fischer, D.P., England, G.C. (2005). Clinical evaluation of postpartum vaginal mucus reflects uterine bacterial infection and the inflammatory re-sponse to endometritis in cattle. Theriogenology. 63, 102–117.

Barlund, C.S., Carruthers, T.D., Waldne, C.L. (2008). A comparison of diagnostic techniques for postpartum endometritis in dairy cattle. Theriogenology. 69, 714–723.

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PDF Downloads: 238
Published
2017-11-05
How to Cite
Katsaraba, O., Dmytriv, O., Kostyshyn, Y., Ivashkiv, R., Kava, S., & Sachuk, R. (2017). Efficiency of treatment of postpartum endometritis of cows with aerosol preparation «Tsefhen». Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sciences, 19(82), 230-234. Retrieved from https://nvlvet.com.ua/index.php/journal/article/view/1395