Bactericidal and disinfective properties of disinfectant «GK-10»
The article presents the results of research on bactericidal properties of the new domestic disinfectant «GK-10», which is a transparent solution of light yellow color, without mechanical inclusions with a specific odor. It is well mixed with water. It is based on alkyl dimethylbenzyl ammonium chloride (QAC) and dodecylbispropylentriamine (1,3-prodadiene) (tertiary amines). Was found bactericidal dilution (BD), bactericidal concentration (BC), phenolic coefficient (FC) and protein index (PI). Thus, the most susceptible to the action of the disinfectant were were gram-negative bacteria E. coli, where cell death occurred at 10 and 30 minute exposures at concentrations of 0.19 and 0.14%, respectively. Due to the action of the disinfectant on the gram-positive bacteria S. aureus, cell death came at these exposures at concentrations 0.27 and 0.19%, respectively. The least susceptible to the action of the disinfectant were vegetative forms of B. subtilis, the death of these bacteria came at concentrations 0.37 and 0.27% at 10 and 30 minutes of exposure, respectively. Effects of disinfectant was over 5.38 and 2.74 times higher on microorganisms of E. coli and S. aureus, respectively, of the decontamination effect of phenol, and in the presence of protein, the activity of the disinfectant is reduced by 6.45 times. The efficiency of the disinfectant for the strains of microorganisms at the disinfestation of the test-object surfaces is determined. It has been established that for test cultures of E. coli and S. aureus 0.05–0.3% of disinfectant concentration is ineffective, and 0.5% its disinfectant concentration for disinfection of hard surfaces in preventive disinfection of premises for animals is insufficient for exposure in 120 minutes. For spore form B. subtilis 1.0% disinfectant concentration was ineffective. 1.0% concentration is effective for aseptic cleaning: slaughterhouses, processing shops, laboratory facilities, means of transporting products of animal origin, soaking clothes before washing, and also for treating surfaces of wood, metal and glazed tile at exposures of 60 minutes and more, and when spore forms of microorganisms, the working concentration of insoluble in disinfection of objects subject to veterinary control should be 3% and above. It has been proved that the disinfectant «GK-10» is effective at a concentration of 0.5% at exposure for 180 minutes and at a concentration of 1.0% at an exposure of 120 minutes for the sanation and preventive disinfection of premises for animals.
Metodychni rekomendatsii (2010). Metody vyznachennia ta otsinky pokaznykiv bezpeky i yakosti dezinfikuiuchykh, myino-dezinfikuiuchykh zasobiv, shcho zastosovuiutsia pid chas vyrobnytstva, zberihannia, transportuvannia ta realizatsii produktsii tvarynnoho pokhodzhennia. Zatverdzheni Derzhkomitetom vetmedytsyny Ukrainy protokol № 1 vid 23.12.2009 roku. Veterynarna dezinfektsiia (Instruktsiia ta metodychni rekomendatsii). Kyiv, 65–152 (in Ukrainian).
Prokudina, N. (2014). Dezinfektant krashche vybyraty vysokoaktyvnyi, bahatofunktsionalnyi, z prolonhovanoiu diieiu, bezpechnyi dlia liudyny y ptytsi. Nashe ptakhivnytstvo. 11, 12–16 (in Ukrainian).
Smolynets,’ I.B., Gutyj, B.V., Khariv, І.І., Petryshak, O.Y., & Lytvyn, R.I. (2016). Pharmaceutical marketing: objectives and types. Scientific Messenger of Lviv National University of Veterinary Medicine and Biotechnologies. 18, 2(69), 151–154 doi:10.15421/nvlvet6929.
Tishyn, O.L., Kopijchuk, G.T., Khomiak, R.V., Khyrivskyy, O.V., & Orynchak, Т.V. (2017). Bactericidal and disinfective properties of disinfectant «Arquadez–plus». Scientific Messenger of Lviv National University of Veterinary Medicine and Biotechnologies. 19(78), 68–73. doi:10.15421/nvlvet7814.
Tishyn, O.L., Kopijchuk, G.T., Khomiak, R.V., Khyrivskyy, O.V., Danko, M.M. (2017). Bactericidal and disinfective properties of disinfectant «Alkisept–100». Scientific Messenger of Lviv National University of Veterinary Medicine and Biotechnologies. 19(73), 61–65. doi:10.15421/nvlvet7313
Tishyn, O.L., Velychko, V.O., & Khomiak, R.V. (2016). Dezinfikuiuchi zasoby virulitsydnoi dii na rynku Ukrainy. Naukovo-tekhnichnyi biuleten Derzhavnoho naukovo-doslidnoho kontrolnoho instytutu veterynarnykh preparativ ta kormovykh dobavok i instytutu biolohii tvaryn. 17(2), 356–364 (in Ukrainian).
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