Influence of sulfur complex on hematological indicators of the rabits

  • A. Z. Dychok-Niedzielska Institute of Animal Biology NAAS, Lviv, Ukraine
  • Y. V. Lesyk Institute of Animal Biology NAAS, Lviv, Ukraine
Keywords: rabbits, blood, nanosulfur, sodium sulphate, hematological indicators


The article presents results on the influence of different amounts of sulfur citrate, manufactured using nanotechnology and sodium sulfate in rabbit diet from 60 to 118 days of age on the hematological parameters of their organism. Studies have been conducted on 30 rabbits of the Hyla hybrid divided into six groups (control and five experimental), 6 animals in each. Animals were kept in regulated microclimate and illumination in mesh cages of 50×120×30 cm. Controlled rabbits fed without restriction a balanced granulated feed with free access to water. The young of the first (E-II), the second (E-II), the third (E-III) and the fourth (E-IV) experimental groups feed the diet of the control group and, during the day, dispensed sulfur citrate from the calculation of 2; 4; 8 and 12 mg S/kg body weight. Rabbits (E-V) of the experimental group fed the diet of the control group and set water with sodium sulfate (Na2SO4) in the amount of 40 mg S/kg body weight. In the preparatory period – 60 days and in the experimental period – at 91 and 118 days of life (31 and 58 days of delivery of supplements), blood samples were collected from the regional anterior vein of rabbits for hematological studies performed using an automatic hematologic analyzer (Orphee Mythic-18, Switzerland). Researches have shown that the administration of citrate sulfur in the amount of 8 mg S/kg of body weight was marked by a greater number of red blood cells and leukocytes, respectively, by 13.4 and 23.3% (P < 0.05) and with a higher level of HCT at 16.2% (P < 0.05), MCH, RDV and MCHC, respectively, 11.1; 14.5 and 2.6% (P < 0.05) on day 58 of the experiment compared with the control group. In the blood of animals in the 2nd experimental group, a higher concentration of hemoglobin < 0.05) was observed at 31 days and a higher HCT < 0.05) level was 58 days compared to control. Thus, the results of the study of the hematological parameters of the body of rabbits indicate their positive changes in the actions of the physiologically substantiated amount of organic sulfur, which contributed to the activation of metabolic processes.


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Acosta, E. (2009). Bioavailability of nanoparticles in nutrient and nutraceutical delivery. Current Opinion in Colloid and Interface Science, 14(1), 3–15. doi: 10.1016/j.cocis.2008.01.002.

Borysevych, V.B., Kaplunenko, V.H., & Kosinov, M.V. (2010). Nanomaterialy v biolohii. Osnovy nanoveterynarii. Posibnyk. K.: VD “Avitsena” (in Ukrainian).

Buiuklu, H., Salii, V., & Yalovenko, A. (2008). Perspektyvy vidrodzhennia haluzi molochnoho i m`iasnoho skotarstva na Khersonshchyni. Tvarynnytstvo Ukrainy, 9–10, 7–8 (in Ukrainian).

De Blas, C., & Wiseman, J. (2010). Nutrition of the Rab-bit. 2nd Edition. Library of Congress Cataloging-in-Publication Data.

Isaac, L.J., Abah, G., Akpan, B., & Ekaette, I.U. (2013). Haematological properties of different breeds and sexes of rabbits. Proc. of the 18th Annual Conf. of Anim. Sci. Assoc. of Nig., 24–27.

Ihedioha, J.T., Okafor, C., & Ihedioha, T.E. (2004). The haematological profile of the Sprague Dawley out bred albino rat in Nsukka. Animal Research Interna-tional, 1(2), 125–132. doi: 10.4314/ari.v1i2.40755.

Chekman, I.S., Ulberh, Z.R., & Malanchuk, V.O. (2012). Nanonauka, nanobiolohiia, nanofarmatsiia. Polihraf plius, Kyiv (in Russian).

Khomyn, M.M., Fedoruk, R.S., & Khrabko, M.I. (2013). Fizioloho-biokhimichnyi vplyv tsytrativ nanochastynok khromu ta selenu v orhanizmi shchureniat. Biolohiia tvaryn, 15(4), 141–149 (in Ukrainian).

Kosinov, M.V., & Kaplunenko, V.H. (2009). Patent Ukrainy na korysnu model № 38391. Sposib otrymannia karboksylativ metaliv “Nanotekhnolohiia otrymannia karboksylativ metaliv”. MPK (2006): C07C 51/41, C07F 5/00, C07F 15/00, C07C 53/126 (2008.01), C07C 53/10 (2008.01), A23L 1/00, B82B 3/00. Opubl. 12.01.2009, biul. № 1/2009. (in Ukrainian).

Nesli, S., & Kokini, J. (2009). Nanotechnology and its applications in the food sector. Trends in Biotechnology, 27(2), 82–89. doi: 10.1016/j.tibtech.2008.10.010.

Official Journal of the European Union L276/33, 2010. Directive 2010/63/EU of The European Parliament and of The Council of 22 September 2010 on the pro-tection of animals used for scientific purposes. 86/609/EC. 20.10.2010.

Papa, A., Emdin, M., Passino, C., Michelassi, C., Battaglia, D., & Cocci, F. (2008). Predictive value of elevated neutrophil-lymphocyte ratio on cardiac mor-tality in patients with stable coronary artery disease. Clin. Chim. Acta, 395(1), 27–31. doi: 10.1016/j.cca.2008.04.019.

Rybarczyk, A., & Łupkowska, A. (2016). Meat quality of mongrel rabbits and the crosses of the California and New Zealand white breeds. Nauka Przyroda Technologie, 10(1), 1–9. doi: 10.17306/J.NPT.2016.1.2

Vernikov, V.M. Arianova, E.A., Gmoshinskij, I.V., Hotimchenko, S.A., & Tutel'jan, V.A. (2009). Nanotehnologii v pishhevyh produktah: perspektivy i problemy. Voprosy pitanija, 78(2), 4–17 (in Russian).

Togun, V.A., Oseni, B.S.A., Ogundipe, J.A., Arewa, T.R., Hammed, A.A., Ajonijebu, D.C., Oyeniran, A., Nwo-sisi, I., & Mustapha, F. (2007). Effects of chronic lead administration on the haematological parameters of rabbit — a preliminary study. Proc. of the 41st Conf. of the Agric. Soc. of Nig., 341.

Zawislak, J., & Świecicka, N. (2015). Analiza czynników wpływających na końcową masę ciała u wybranych ras królików. Journal of Central European Agriculture, 16(2), 28–37. doi: 10.5513/JCEA01/16.2.1582.

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Dychok-Niedzielska, A., & Lesyk, Y. (2018). Influence of sulfur complex on hematological indicators of the rabits. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sciences, 20(92), 203-208.