To the method of study of preparations that are often used in anesthetic prac-tice for surgical interventions in small animals


Keywords: anesthesia, propofol, ketamine, medetomedine, butorphanol, sleep, myorelaxation, analgesia

Abstract

A review of the literature on the study of medicines that is often used in anesthetic practice for surgical interventions in small animals is made. A large arsenal of pharmacological agents and the possibility of their use in various combinations now allow the use of a variety of anesthetic methods. The choice of the method of anesthesia should correspond, above all, to the patient, as well as the nature and duration of the planned operation. As a matter of fact, an anesthetic method should be used to ensure maximum animal safety. It is known that in order to provide effective anesthesia you need: sleep, muscle relaxation (relaxation of muscles), analgesia (anesthesia). To ensure of these three requirements, a number of preparations are used: propofol, ketamine (dissociative anesthetics: zoletil-tieletamine hydrochloride, zelozepam hydrochloride), alpha-2 antagonists – xylazine (xylan, sedacil, sedazin, meditin), opioids (fentanyl, morphine, butorphanol). The characteristic of preparations propofol, ketamine, medetomedine, butorphanol is given. In view of the foregoing, we conclude that a large number of medicinal products are used in operative interventions in estheological practice. However, it is important to emphasize that only a combination of the above preparations among ourselves can provide effective anesthesia, which will increase the analgesic action, reduce the toxicity of these preparations and faster wound healing and recovery.

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References

Andreeva, N.L., & Nechaev, A.Ju. (2001). Farmakologicheskoe vozdejstvie na adrenoreaktivnye sistemy i primenenie stimuljatora a2-adrenoreceptorov ksilazina v veterinarnoj anesteziologii. SPb.: SPbGAVM (in Russian).

Betshart-Vol'fensberger, R., Stekol'nikov, A.A., & Nechaev, A.Ju. (2010). Veterinarnaja anesteziologija: uchebnoe posobie. SPb.: SpecLit (in Russian).

Kirk, R., & Bonagura, D. (2005). Sovremennyj kurs veterinarnojmediciny Kirka. M.: Akvarium-Print (in Russian).

Kozlovskaja, N.G., Ivashko, E.S., & Turovnikova, E.V. (1996). Osnovnye principy anesteziologii. Konferencija po aktual'nym problemam profilaktiki, diagnostiki i lechenija boleznej melkih domashnih zhivotnyh. 26 marta 1996, Moskva (in Russian).

Kornjushenkov, E.A. (2009). Propovan, kakosnovnoj komponent total'noj vnutrivennoj anestezii u sobak. Rossijskij veterinarnyj zhurnal. KolosS, 2, 2–4 (in Russian).

Kornjushenkov, E.A., & Gimel'farb, A.I. (2010). Ispol'zovanie preparata Propovan v kachestve komponenta vnutrivennoj anestezii u koshek. Rossijskijveterinarnyj zhurnal. KolosS, 2, 28–32 (in Russian).

Saltanov, A.I. (1997). Aktual'nye voprosy sovremennoj vnutrivennoj anestezii. Anesteziologija i reanimatologija, 6, 77–79 (in Russian).

Harkevich, D.A. (2004). Farmakologija. GJeOTAR-MED (in Russian).

Alony, Y., & White, R. (1996). Total intravenous anesthesia with propofol/ketamine in the dog. A prospective case series. XXIst Congress of the world small animal veterinary association – WSAVA. Jerusalem, Israel.

Andress, J.L., Day, T.K., & Day, D. (1995). The effects of consecutive day propofol anesthesia on feline red blood cells. VetSurg, 24(3), 277–282. https://www.ncbi.nlm.nih.gov/pubmed/7653043.

Bley, R., Roos, M.,Price, J., Ruess-Melzer, K., Buchholz, J., Poirier, V., & Kaser-Hotz, B. (2007). Clinical assessment of repeated propofol-associated anesthesia in cats. Journal of the American Veterinary Medical Association, 231(9), 1347–1353. doi: 10.2460/javma.231.9.1347.

Brearley, J.C., Kellagher, R.E.B., & Hall, L.W. (1988). Propofol Anaesthesia in Cats. Journal of Small Animal Practice, 29(5), 315–322. doi: 10.1111/j.1748-5827.1988.tb02290.x.

Fayyaz, S., Kerr, C.L., Dyson, D.H., & Mirakhur, K.K. (2009). The cardiopulmonary effects of anestetic induction with isoflurane, ketamine-diazepamorpropofol-diazepamin the hypovolemic dog. Veterinary Anaesthesia and Analgesia, 36(2), 110–123. doi: 10.1111/j.1467-2995.2008.00437.x.

Hofmeister, E.H., Weinstein, B., Berger, D., et al. (2009). Effects of graded doses of propofol for anesthesia induction on cardiovascular parameters and intraocular pressures in normal dogs. Vet Anaesth Analg., 36(5):442–448. doi: 10.1111/j.1467-2995.2009.00482.x.

Mendes, G.M., & Selmi, A.L. (2003). Use of a combination of propofol and fentanyl, alfentanil, or sufentanil for total intravenous anesthesia in cats. J Am Vet Med Assoc., 223(11): 1608–1613. https://www.ncbi.nlm.nih.gov/pubmed/14664447.

Morgan, D.W., & Legge, K. (1989). Clinical evaluation of propofol as an intravenous anaesthetic agent in cats and dogs. Vet Rec, 124(2), 31–33. https://www.ncbi.nlm.nih.gov/pubmed/2783794.

Pascoe, P.J., Ilkiw, J.E., & Frischmeyer, K.J. (2006). The effect of the duration of propofol administration on recovery from anesthesia in cats. Vet Anaesth Analg, 33(1), 2–7. doi: 10.1111/j.1467-2995.2005.00216.x.

Richard Adams, H. (2001). Veterinary pharmacology and therapeutics – 8 thed. Iowa State University Press, 293–294.

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Published
2018-12-10
How to Cite
Nazaruk, N. (2018). To the method of study of preparations that are often used in anesthetic prac-tice for surgical interventions in small animals. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sciences, 20(92), 218-221. https://doi.org/10.32718/nvlvet9245

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