Changes of hematological parameters of in blood in cats ill with microsporium
There has been a massive tendency for cats to be kept as pets in Ukraine in recent years. The frequency of their diseases has also increased at the same time. Cats most often come into the homes of people from the street, from volunteers, rarely from nurseries. Due to this, Doctors often receive cats ill for microsporia, which is caused by fungi of the genus Microsporum and is one of the most common anthropozoonous diseases. The treatment process is carried out by a complex method. Analysis of the recommendations of various authors on the treatment of microsporia indicates the lack of immunostimulants in the conduct of a complex of therapeutic and preventive measures. Hematological studies were performed in order to find out the immune reactivity of the cats' organism during microsporia. The research was conducted on clinically healthy and cats ill for microspores. The obtained results of research showed that in cats with microsporia changes in morphological composition of blood were characterized by signs of anemia, leukopenia and lymphocytopenia. Changes in the structure of neutrophils were found in the type of vacuum and toxigenic grains in cats ill for microsporia. The toxic grains of neutrophils occur inside the cell as a result of physicochemical changes in the protein structure of the cytoplasm. Such cells can not provide phagocytosis of foreign agents and thus reduce the immune activity of the organism in cats ill for microsporium. A marked change in the shape of erythrocytes, which is characteristic of anemia, that is, erythrocytes-octantocytes with corneas by Jolly inclusions. Jolly's bodies are the remnants of the nucleus that have survived in erythrocytes because of the broken destruction of the normoblast nucleus. The obtained results indicate that the course and manifestation of microsporia in cats affects the immune status of the organism.
Chermette, R., Ferreiro, L., & Guillot, J. (2008). Dermatophytoses in animals. Mycopathologia, 166(5–6), 385–405. doi: 10.1007/s11046-008-9102-7.
da Costa, F.V., Farias, M.R., Bier, D., de Andrade, C.P., de Castro, L.A., da Silva, S.C., & Ferreiro, L. (2013). Genetic variability in Microsporum canis isolated from cats, dogs and humans in Brazil. Mycoses, 56(5), 582–588. doi: 10.1111/myc.12078.
Di Mattia, D., Fondati, A., Monaco, M., Pasquetti, M., & Peano, A. (2019). Comparison of two inoculation methods for Microsporum canisculture using the toothbrush sampling technique. Vet Dermatol, 30, 60–e17. doi: 10.1111/vde.12705.
Golovina, N.P. (1988). Dermatomikozy sobak i koshek v uslovijah gorodov. Veterinarija, 1, 59–61 (in Russian).
Karput, I.M. (1986). Gematologicheskij atlas sel'sko-hozjajstvennyh zhivotnyh. Minsk: Uradzhaj (in Rus-sian).
Kirk, R., & Bonahura, Dzh. (2014). Suchasnyi kurs vet-erynarnoi medytsyny. Moskva. Akvarium Prynt (in Ukrainian).
Kondrahin, I.P., Arhipov, A.V., & Levchenko, V.I. (2004). Metody veterinarnoj klinicheskoj laboratornoj diagnostiki: Spravochnik. M. Kolos (in Russian).
Kozinca, G.I., & Makarova, V.A. (1997). Issledovani sistemy krovi v klinicheskoj praktike. pod red. M. Tri-ada-H (in Russian).
Kurasova, V.V., Kostin, V.V., & Malinovskaja, L.S. (1971). Metody issledovanija v veterinarnoj mikologii. M. Kolos (in Russian).
Kysera, Ya.V., Storchak, Yu.G., & Gutyj, B.V. (2018). Experimental study of immunoprophylactic anti-pneumococcal medicine and its immunogenic proper-ties. Ukrainian Journal of Ecology, 8(1), 307–316. doi: 10.15421/2018_216.
Khariv, M.I. & Hutyi, B.V. (2017). Dynamika fahotsytarnoi aktyvnosti neitrofiliv u shchuriv za umov oksydatsiinoho stresu ta dii liposomalnoho preparatu. Biolohiia tvaryn, 19(1), 119–124. doi: 10.15407/animbiol19.01.119 (in Ukrainian).
Mazurkevych, A.I. (2012). Fiziolohiia tvaryn. Kyiv: Nova knyha (in Ukrainian).
Mejer, D. & Harvi, D. (2007). Veterinarnaja laboratornaja medicina. Interpretacija i dіagnostika. Moskva: Sofion (in Russian).
Moriello, K.A., Coyner, K., Paterson, S., & Mignon, B. (2017). Diagnosis and treatment of dermatophytosis in dogs and cats: Clinical Consensus Guidelines of the World Association for Veterinary Dermatology. Vet Dermatol, 28(3), 266–e68. doi: 10.1111/vde.12440.
Peterson, S. (2008). Shkirni khvoroby kotiv. Moskva: Akvarium-Prynt (in Ukrainian).
Pototskyi, M.K. (2000). Dermatomikozy. Veterynarna medytsyna Ukrainy, 11, 20 (in Ukrainian).
Spesivceva, N.A. (1960). Mikozy i mikotoksikozy zhivotnyh. M. Sel'hozizdat (in Russian).
Tutel'jan, V.A., & Kravchenko, L.V. (1985). Mikotoksiny. M. (in Russian).
Vlizlo, V.V., Slivinska, L.H., Maksymovych, I.A., Leno, M.I., & Halias, V.L. (2014). Laboratorna diahnostyka u veterynarnii medytsyni. Dovidnyk. 2-he vydannia. Lviv (in Ukrainian).
Yu, J., Wan, Z., Chen, W., Wang, W., & Li, R. (2004). Molecular typing study of the Microsporum canis strains isolated from an outbreak of tinea capitis in a school. Mycopathologia, 157(1), 37–41. https://www.ncbi.nlm.nih.gov/pubmed/15008343
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