Comparative effectiveness of different therapeutic methods for calves with abomazoenteritis


Keywords: calves, abomazoenteritis, alanine aminotransferase, aspartate aminotransferase, peroxide lipid oxidation, metabolic intoxication

Abstract

The article presents the results of the comparative effectivness of different treatment regimens of calves with abomazoenteritis. Three groups of black-and-white-breed calves of the age of 1–1.5 months were formed for 5 animals in each of the 1st and 2nd experimental (patients with abomazoenteritis) and control – clinically healthy animals. Treatment of sick calves in experimental groups was performed using diet therapy, antimicrobial and rehydration therapy. Animals of the second experimental group, in addition, used detoxification means and Sel-Plex. It was found that calving treatment with the use of diet, antimicrobial, detoxication, rehydration therapy helped to eliminate the main clinical symptoms of the disease. Positive changes were established during laboratory blood tests: the number of red blood cells, leukocytes, hemoglobin, total protein and hematocrit was normalized. In animals with abomazoenteritis, during treatment decreased the activity of transaminases decreased, the content of TBA-active products and medium-weight molecules. The treatment was effective and contributed to a reduction in the duration of their clinical recovery, but the normalization of biochemical parameters was more pronounced in animals of the second experimental group. Application together with antimicrobial and rehydration means of Sel-Plex and detoxification drugs accelerated the restoration of basic biochemical parameters (aspartate aminotransferase, alanine aminotransferase, TBK-active products and medium-weight molecules) to normal, and therefore reduced the metabolic intoxication of the animals organism.

Downloads

Download data is not yet available.

References

Aghakeshmiri, F., Azizzadeh, M., Farzaneh, N., & Gorjidooz, M. (2017). Effects of neonatal diarrhea and other conditions on subsequent productive and reproductive performance of heifer calves. Vet Res Commun, 41(2), 107–112. doi: 10.1007/s11259-017-9678-9.

Andreeva, L.I., Kozhemjakin, L.A., & Kishkun, A.A. (1988). Modifikacija metoda opredelenija lipidov v teste s tiobarbiturovoj kislotoj. Laboratornoe delo, 11, 41–43 (in Russian).

Belko, A.A., Shparkovich, M.V., & Pajterova, V.V. (2008). Osobennosti klinicheskogo projavlenija abomazojenterita u teljat. Vіsnik Bіlocerkіv. derzh. agrar. un-tu: zb. nauk. prac'. Bіla Cerkva, 56, 22–26 (in Russian).

Berezovskyi, A.V., Fotina, T.I., Ulko, L.H., Nechyporen-ko, O.L., & Titov, Ye.M. (2016). Etiolohichna struktu-ra hostrykh shlunkovo–kyshkovykh zakhvoriuvan te-liat, Naukovyi visnyk LNUVMBT imeni S.Z. Gzhytskoho, 18, 3(71), 148–151. doi: 10.15421/nvlvet7133 (in Ukrainian).

Danchuk, V.V. (2006). Peroksydne okysnennia u silskohospodarskykh tvaryn i ptytsi. Kamianets-Podilskyi: Abetka (in Ukrainian).

Directive 2010/63/eu of the european parliament and of the council of 22 September 2010 on the protection of animals used for scientific purposes. Official Journal of the European Union. L276/33.

20.10.2010. https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=celex%3A32010L0063.

Karimov, I.Z. (2005). Okislitel'naja modifikacija belkov i perekisnoe okislenie lipidov v razvitii meta-bolicheskoj intoksikacii pri patologii. Lab. Diagnosti-ka, 31(1), 7–13 (in Russian).

Kurtiak, B.M., Romanovych, M.S., Pundiak, T.O., Ro-manovych, L.V., Sobko, H.V., Romanovych, M.M. (2018). Umovno patohenna mikroflora ta yii rol v eti-olohii hostrykh rozladiv travlennia z oznakamy diarei novonarodzhenykh teliat. Naukovyi visnyk LNUVMB imeni S.Z. Gzhytskoho, 20(83), 304–307. doi: 10.15421/nvlvet8361 (in Ukrainian).

Nikolajchik, V.V., Moin, V.M., Kirkovskij, V.V. i dr. (1991). Sposob opredelenija “srednih molekul”. Lab. Delo, 10, 13–18 (in Russian).

Piatnychko, O.M., Lisova, N.E., Shkodiak, N.V. ta in (2013). Morfolohichni, imunolohichni ta biokhimichni pokaznyky krovi khvorykh na hastroenteryt teliat za umov anty-biotykoterapii. Vet. Medytsyna, 97, 342–344. https://elibrary.ru/item.asp?id=22268134 (in Ukrainian).

Slobodiuk, N.M. (2018). Zastosuvannia fluorkhinoloniv u praktytsi veterynarnoi medytsyny Ukrainy. Naukovyi visnyk LNUVMB imeni S.Z. Gzhytskoho, 20(87), 89–93. doi: 10.32718/nvlvet9210 (in Ukrainian).

Stetsko, T.O. Muzyka, V.P. & Hunchak, V.M. (2018). Krytychno vazhlyvi antymikrobni preparaty dlia vet-erynarnoi medytsyny. Naukovyi visnyk LNUVMB imeni S.Z. Gzhytskoho, 20(87), 19–26. doi: 10.15421/nvlvet8704 (in Ukrainian).

Teixeira, A.G., Stephens, L., Divers, T.J., Stokol, T., & Bicalho, R.C. (2015). Effect of crofelemer extract on severity and consistency of experimentally induced enterotoxigenic Escherichia coli diarrhea in newborn Holstein calves. J Dairy Sci., 98(11), 8035–8043. doi: 10.3168/jds.2015-9513.

Tsukano, K., & Suzuki, K. (2019). Plasma amino acid abnormalities in calves with diarrhea. J Vet Med Sci., 81(4), 517–521. doi: 10.1292/jvms.18-0645.

Zharkoj, B.L. (2004). Vzaimosvjaz' intensivnosti pro-cessov svobodno¬radikal'nogo okislenija i pokazate-lej immunnogo statusa u teljat. Svobodnye radikaly, antioksidanty i zdorov'e zhivotnyh : mate-rialy mezhdunar. nauch.-prakt.konf., 21–23 sentjabrja 2004 g. Voronezh, 36–40 (in Russian).

Zinko, H.O. (2017). Imunnyi status teliat, khvorykh na hastroenteryt. Naukovyi visnyk LNUVMB imeni S.Z. Gzhytskoho, 19(82), 61–65. doi: 10.15421/nvlvet8213 (in Ukrainian).

Zinko, H.O. (2017). Peroksydno-okysni protsesy ta stan systemy antyoksydantnoho zakhystu u teliat za hastroen-terytu. Ahrarnyi visnyk Prychornomoria. Veterynarni nauky, 83, 86–90 (in Ukrainian).

Zinko, H.O., & Slivinska, L.H. (2015). Vplyv preparativ Selenu ta Hermaniiu na okremi lanky patohenezu hastroenterytu u teliat. Biolohiia tvaryn, 17(2), 57–64. doi: 10.15407/animbiol17.02 (in Ukrainian).

Abstract views: 0
PDF Downloads: 0
Published
2019-07-30
How to Cite
Slivinska, L., Demydjuk, S., Lukashchuk, B., & Zinko, H. (2019). Comparative effectiveness of different therapeutic methods for calves with abomazoenteritis. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sciences, 21(94), 20-24. https://doi.org/10.32718/nvlvet9404