Application of aflubine in the treatment scheme for pigs with respiratory syndrome

Keywords: aflubin, ceftriaxone, amoxicillin, pigs, respiratory diseases, treatment


The article investigates into changes of clinical parameters and leukograms of pigs with respiratory syndrome in comparison with the use of unprotected antibiotics penicillins (amoxicillin suspension 15%), third generation cephalosporins (ceftracone) and complex therapy (ceftracone in combination with oral administration of aflubin). In pigs, many pathogens (bacteria and viruses) parasitize, which can affect the upper respiratory tract. Failure to observe the rules for the use of antibiotics for the treatment of animals leads to the formation of resistant forms of microorganisms. Therefore, the introduction of treatment regimens that simultaneously have a polyvectoral action and stimulate the functioning of the body systems (as well as the work of homeopathy), allows you to achieve a positive therapeutic effect more quickly. In a private household where pigs are kept fattened, the disease of pigs with respiratory syndrome is registered, mostly in 1428 days after purchase. In such animals, body temperature increased to 41.0–41.1 degrees Celsius, fever, weakness, lack of appetite, animals buried in the litter, and in the leukoformula, a slight increase (by 4.8% excess of the upper physiological limit) of lymphocytes and a slight decrease in segmental nuclei neutrophils (by a maximum 1.2% below the minimum physiological level). From pigs with respiratory syndrome, on the principle of analogues, formed three groups of 4 animals. For treatment, the first group used emulsion amoxicillin 15% from the rate of 1 cm3/10 kg of body weight of the animal, the second - ceftriaxone (20 mg/kg body weight 2 times a day for 35 days), the third with ceftriaxone aflubin at the expense 10 drops (0.5 cm3/60 kg body weight for 3 days). Pigs eagerly consumed the drug when we took the drug into the syringe and orally, inserting the cannula for the lower lip. Based on randomized controlled trials, the simultaneous use of ceftriaxone intramuscularly and oral administration of Aflubine every 4 hours (during the first day), and subsequently with an interval of 12 hours for 3 days, contributes to complete clinical healing within the first day after commencing the use of drugs and shortens the treatment period pigs in 2 times, than the introduction of only ceftraxone. Oral use of aflubin in pigs administered intramuscularly amoxicillin provided cure for the next 12 hours, manifested by the restoration of appetite. Consequently, administration of aflubine with ceftriaxone and amoxicillin provides a reduction in the duration of pigs’ treatment with respiratory syndrome, which will reduce the use of antibiotics. Therefore, we consider it expedient to introduce into the schemes of this homeopathic remedy treatment in the therapy of pigs with symptoms of the infectious etiology respiratory system.


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AFLUBІN®, іnstrukcіja zastosuvannja (UA/1952/02/01). (Nakaz MOZ №85 vіd 17.01.2018) (in Ukrainian).

Camerlink, I., Ellinger, L., Bakker, E.J. & Lantinga, E.A. (2010). Homeopathy as replacement to antibiotics in the case of Escherichia coli diarrhoea in neonatal piglets. Homeopathy, 99(1), 57–62. doi: 10.1016/j.homp.2009.10.003.

Doehring, C., & Sundrum, A. (2016). Efficacy of homeopathy in livestock according to peer-reviewed publications from 1981 to 2014. Vet Rec., 179(24), 628. doi: 10.1136/vr.103779.

Fortuoso, B.F., Geberta, R.R., Grissa, L.G. et al. (2018). Reduction of stool bacterial counts and prevention of diarrhea using an oral homeopathic product in newborn lambs. Microbial Pathogenesis, 127, 347–351. doi: 10.1016/j.micpath.2018.12.022.

Fortuoso, B.F., Volpato, A., Rampazzo, L., Glombowsky, P., Griss, L.G., Galli, G.M., & da Silva, A.S. (2018). Homeopathic treatment as an alternative prophylactic to minimize bacterial infection and prevent neonatal diarrhea in calves. Microbial Pathogenesis, 114, 95–98. doi: 10.1016/j.micpath.2017.11.04.

Mathie, R.T., Baitson, E.S., Hansen, L., Elliott, M.F., & Hoare, J. (2010). Homeopathic prescribing for chronic conditions in equine veterinary practice in the UK. Vet Rec., 166(8), 234–238. doi: 10.1136/vr.b4764.

Mihailović, V., Matić, S., Mišić, D. et al. (2013). Chemical composition, antioxidant and antigenotoxic activities of different fractions of Gentiana asclepiadea L. roots extract. EXCLI Journal, 12, 807–823.

Pogodaeva, N.N., Vereshhagin, A.L., Gorshkov A.G. i dr. (2000). Alkaloidnyj sostav nekotoryh vidov Aconitum L. flory Sibiri. Rast. resursy. 36, 2 (in Russian).

Radomskaia, N.A., & Belevskaya, R.G. (2017). Homeopathy. Health resources. Russian journal of resources, conservation and recycling, 1(4), 1–11. doi: 10.15862/04RRO117 (in Russian).

Shavel', І. (2012). Tsiliushchi roslyny Ukrainy. Lviv (in Ukrainian).

Vekіrchik, K.M. (2017). Otrujnі lіkars'kі roslini.

Weiermayer, P. (2018). Wound Healing Disorder in a Horse, Associated With Antimicrobial-Resistant Bacteria, Resolved With a Homeopathic Medicine – A Case Report. Journal of Equine Veterinary Science, 67, 37–43. doi: 10.1016/j.jevs.2018.02.027.

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Rybachuk, Z., Galatyuk, O., & Romanyshyna, T. (2019). Application of aflubine in the treatment scheme for pigs with respiratory syndrome. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sciences, 21(94), 86-91.