Morphological particulars of the liver of laying hens of cross “Lohmann Brown” under hepatosis

Keywords: laying hens, age dynamics, liver, hepatocytes, histostructure, hepatosis, obesity.


The article presents the results of histological examinations of the liver of laying hens at age 166, 300 and 530 days, in which according to the results of biochemical analysis of blood serum revealed a subclinical course of hepatosis. The purpose of our study was the early diagnosis of this pathology and the study of the histological structure of the liver in different periods of poultry productivity. The work was performed at LLC Agro Firm “Zagai” of Kamianka-Buzkyi district of Lviv region. Autopsy and examination of histological specimens were performed at the Department of Normal and Pathological Morphology and Forensic Veterinary at Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies Lviv. The macroscopic examination of the liver showed that in part of laying hens at 166 days of age, in most of laying hens at 300 days old and in all of laying hens at 530 days old examined, the liver was slightly enlarged, of a sluggish consistency and unevenly colored. It should also be noted that, in addition to severe dystrophic changes in the liver, 530 days of laying hens also showed signs of general obesity. The study of histological specimens installed that in part of laying hens at 166 days of age, the liver lobules were disordered, in resulting was disrupted their beam structure. At the same time, cytoplasm of hepatocytes is somewhat cloudy and visible granularity. In laying hens at age 300 and 530 days installed the discomplexation of the beam structure of the organ and the presence of small and large droplets of fat vacuoles in hepatocytes are indicated, which indicate about the development of fatty dystrophy. The results of the morphological study indicate the presence in the liver of laying hens signs of acute and chronic pathological processes, which with age are complicated by dystrophic changes of the organ.


Download data is not yet available.


Bancroft, J. D., Layton, C., & Suvarna, S. K. (2013). Bancroft’s Theory and Practice of Histological Techniques. 7th edition. Churchill Livingstone: Elsevier, 672. 978-0-7020-5032-9.

Bella, D. L., Hirschberger, L. L., Kwon, L. L. еt al. (2002). Cysteine metabolism in periportal and perivenous hepatocytes: perivenous cells have greater capacity for glutathione production and taurine synthesis but not for cysteine catabolism. Amino Acids, 23, 453–458. doi: 10.1007/s00726-002-0213-z.

Bodrova, L. F. (2009). Gistologicheskie i gistohimicheskie osobennosti struktury pecheni kur, poluchavshih nizkokalorijnye kormosmesi i raciony s raznym urovnem obmennoj jenergii. Dostizhenija nauki i tehniki APK, 3, 51–53. (in Russian).

Butler, E. J. (1976). Fatty liver diseases in the domestic fowl. Avian Pathology, 5(1), 1–14. doi: 10.1080/03079457608418164.

Danilov, A. P., & Berkovich, V. I. (1975). Vozrastnye osobennosti morfologii i gistohimii pecheni kur. Zemlja sib. dal'nevost. Omsk, 12, 9–10 (in Russian).

Dunets, V. Iu., & Slivinska, L. H. (2017). Profilaktyka khvorob pechinky u kurei yaiechnoho napriamku produktyvnosti. Nauk. visnyk LNUVMBT imeni S. Z. Gzhytskoho, 19(73), 55–60. doi: 10.15421/nvlvet7312 (in Ukrainian).

Dunets, V. Iu., & Slivinska, L. H. (2018). Klinichna syndromatyka kurei-nesuchok krosu “Loman-Braun” v umovakh hospodarstva. Nauk. visnyk LNUVMBT imeni S. Z. Gzhytskoho, 20(83), 341–346. doi: 10.15421/nvlvet8368 (in Ukrainian).

El-Katcha, M. I., Soltan, M. A., El-Naggar, K., El-Shobokshy, S. A., & El-Erian, M. A. (2019). Laying performance, fat digestibility and liver condition of laying hens supplemented with vitamin B12 or biotin and/ or bile acids in diet. Slov Vet Res, 56(22), 341–352. doi: 10.26873/SVR-773-2019.

Erehina, G. N. (1990). Mikromorfologicheskie osobennosti stroenija pecheni kur. Sostojanie i razvitie morfologicheskih issledovanij domashnih i dikih ptic. Cheljabinsk, 41–43 (in Russian).

Hohlov, I. V. (2007). Morfogenez patologii pecheni u kur v vozrastnom aspekte. Avtoreferat dissertacii na soiskanie uchenoj stepeni kandidata veterinarnyh nauk. Ekaterinburg: UrGSHA, 3–5 (in Russian).

Horalskyi, L. P., Khomych, V. T., & Kononskyi, O. I. (2005). Osnovy histolohichnoi tekhniky i morfofunktsionalni metody doslidzhen u normi ta pry patolohii. Zhytomyr: “Polissia” (in Ukrainian).

Kelberg, N. A., & Sadovnikov, N. V. (2010). The role of the liver in the metabolism of birds. The morphological changes in the poultry liver while using anti homotoxic therapy. Agrarian Bulletin of the Urals, 1(67), 60–63.

Melnyk, A. Iu. (2015). Analiz i perspektyvy haluzi ptakhivnytstva Ukrainy, poshyrennia ta klasyfikatsiia metabolichnykh khvorob silskohospodarskoi ptytsi. Nauk. visnyk veterynarnoi medytsyny. Bila Tserkva, 2, 67–73. (in Ukrainian).

Nikitin, Ju. P., Kurilovich, A. I., & Davyshhin, G. S. (1985). Pechen' i lipidnyj obmen. Novosibirsk: Nauka (in Rus-sian).

Sarkisova, D. S., & Perova, Ju. L. (1996). Mikroskopicheskaja tehntehnika: Rukovodstvo. M.: Medicyna (in Russian).

Vashchyk, Y., Shcherbyna, R., Parchenko, V., Bushueva, İ., Gutyj, B., Fotina, H., Fotina, T., & Stronskyi, Y. (2020). Histological study of a corrective influence of a compound potassium 2-((4-amino-5-(morpholinomethyl)- 4h-1,2,4-triazol-3-yl)thio) ace-tate (pkr-173) on the state of chicken's liver under in-fection by pseudomonas aeruginosa. Journal of Faculty of Pharmacy of Ankara University, 44(1), 1–17. doi: 10.33483/jfpau.567757.

Vrakin, V. F., & Sidorova, M. V. (1999). Anatomija i gistologija domashnej pticy. M.: Kolos (in Russian).

Abstract views: 3
PDF Downloads: 6
How to Cite
Yaremchuk, V., Slivinska, L., & Stronskyi, Y. (2020). Morphological particulars of the liver of laying hens of cross “Lohmann Brown” under hepatosis. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sciences, 22(97), 69-73.