Influence of complex action of probiotic and specific prophylaxis of associated mucosal diseases on some quantitative traits of dairy cattle performance
The article presents the results of studies of indicators of reaching the age of the first calving of repair heifers of the Ukrainian red dairy breed under the conditions of use of the complex scheme of specific immunoprophylaxis and preparation “Multibacterin veterinary suspension”.The research was conducted in the conditions of the industrial complex for milk production of Dolinskoye LLC, Odessa region. The subjects of the study were groups-analogues of breeding heifers and the firstborn of the genotype.The assessment of repair young growth indicators was performed taking into account the following indicators: age of fertile insemination, months; age of first calving, months; milk production for 100 and 305 days of the first lactation, kg. For the functional evaluation of the digestive status of animals used to determine the transit of feed, in % and the assessment of acid-base status of faeces, pH unit. The following indicators were investigated in the serum of repair calves of mating age: total protein, g/l; albumin, g/l; globulin, g/l; glucose, mmol/l; urea, mmol/l; alkaline phosphatase, units/l and liver enzymes (ALT and AST, units/l).The economic efficiency of the results of the studies was calculated according to the indicator “average hope of one cow for 305 days of the first lactation, kg”. It was found that, due to the positive simultaneous effect of probiotic protection of the intestinal mucous membranes, repair heifers showed a higher growth and development rate and the first calving had 28.07 months, which is 2.31 months (8.45 %) earlier than in control (P < 0.001).The optimization of the technology of growing heifers for the use in the scheme of specific immunoprophylaxis of a probiotic drug – immunomodulator, which feed use had a prolonged positive effect not only on the growth parameters of young animals, but also on the increase of milk productivity per first lactation was experimentally proved.Calculations of cost-effectiveness of research results showed that the maximum increase in production (+ 9.10 %) was obtained from the firstborn of the experimental group born to cows mothers older than two lactations, where the scheme of specific prevention of associated diseases was carried out for repair heifers with previous normophilic laceration probiotic feed preparation.
Biben, I. A. (2016). Influence of a biotic preparation from crops and on the immune response of broiler chickens. Scientific and Technical Bul. IBT and DNKI veteri-naryproductsandfeedadditives, 17(2), 181–186 (in Ukrainian).
Costerton, J. W. (2007). The Biofilm Primer. Berlin: Springer. https://www.springer.com/gp/book/9783540680215.
Cutting, S. M. (2011). Bacillus probiotics. Food Microbiol, 28(2), 214–220. doi: 10.1016/j.fm.2010.03.007.
Davey, M. E., & O”Toole, G. A. (2000). Microbial bio-films: from ecology to molecular genetics. Microbiol Mol Biol Rev, 64(4), 847–867. doi: 10.1128/mmbr.64.4.847-867.2000.
Dubuc, J., Duffield, T. F., Leslie, K. E., Walton, J. S., & LeBlanc, S. J. (2010). Risk factors for postpartum uterine diseases in dairy cows. J Dairy Sci., 93(12), 5764–5771. doi: 10.3168/jds.2010-3429.
Guidelines for the use of the drug Multibacterin veterinary (mono- and poly component probiotics). Approved by the Scientific Council of the State Scientific Research Institute of Veterinary Medicines and Feed Additives (Minutes No. 2 of February 12, 2003).
Gutyj, B., Grymak, Y., Hunchak, V., Mysak, A., Nazaruk, N., Brezvyn, O., Hariv, I., Shcherbatyy, A., Semeniv, B., Bushueva, I., Parchenko, V., Kaplaushenko, A. (2018). Preclinical searches of the preparation Thireomagnile. Ukrainian Journal of Ecology, 8(1), 688–695. doi: 10.15421/2018_267.
Hoibya, N., Bjarnsholt, T., Givskov, M., Molin, S., & Cio-fu, O. (2010). Antibiotic resistance of bacterial bio-films. Int. J. of Agents., 35(4), 322–332. doi: 10.1016/j.ijantimicag.2009.12.011.
Humenny, O. G. (2001). Some indicators of immunologi-cal reactivity of the body of cows and heifers, patients with IRT-PVV, with the combined use of vaccines and immunostimulants. Veterinary medicine of Ukraine, 11, 34–35 (in Ukrainian).
Humenny, O. G., & Morozov, M. G. (2007). Forms and clinical manifestation of IRT – PVV in the farms of Odessa region. Agrarian Bulletin of the Black Sea: Coll. of sciences. works of the Odessa State Tax Ad-ministration. Veterinary Science, 39, 48–53 (inUkrain-ian).
Instruction on artificial insemination of cows and heifers. K., 2001, 38 p. (in Ukrainian).
Jian, L. (2002). Bacterial Resistance to Antimicrobials: Mechanisms, Genetics, Medical Practice and Public Health. Biol. Let., 24(10), 801–805.
Kasimanickam, R., Koziv, R., & Lototskiy, V. (2016). Postpartum uterine diseases in dairy cows. Visnyk Bi-locerkiv. derzh.agrar. in-tu. Bila Cerkva, 2, 11–16.
Khalak, V. I., Gutyj, B. V., & Stadnits’ka, O. I. (2019). Feeding and meat qualities of young pigs of different origin and intensity of formation in early ontogenesis. Scientific Messenger of Lviv National University of Veterinary Medicine and Biotechnologies. Series: Ag-ricultural sciences, 21(91), 10–15. doi: 10.32718/nvlvet-a9102.
Kreft, J.-U. (2009). Biofilms promote altruism. Microbiol-ogy, 150(8), 2751–2760. doi: 10.1099/mic.0.26829-0.
Kudrin, A. G. (2006). Blood enzymes and prediction of the productivity of dairy cattle. Publishin ghouse of FGOU VPO. Michurinsk GAU (in Russian).
Lakin, H. F. (1990). Biometriya: uchebnoe posobiye [dlia biol. Ssets. vuzov]. Moskow, Vysshaya shkola (in-Russian).
Moons, P., Michiels, C.W., & Aertsen, A. (2009). Bacterial interactions in biofilms. Crit. Rev. Microbiol., 35(3), 157–168. doi: 10.1080/10408410902809431.
Moskaleva, E. N. (2019). Influence of various factors on the natural resistance of calves. Sat. Scientific article son the mat. Int. scientific and practical conf. 70th anniversary of the Republican Unitary Enterprise “Scientific and Practical Center of the National Acad-emy of Sciences of Belarus for Livestock”, Zhodino, December 19–20, 2019, Minsk, 155–159 (in Russian).
Patel, R., & DuPont, H. L. (2015). New approaches for bacteriotherapy: Prebiotics, new generation probiotics, and synbiotics. Clin. Infect. Dis., 60(2), 108–121. doi: 10.1093/cid/civ177.
Rublenko, M. V., & Vlasenko, S. A. (2011). Health Prob-lems for High-Performance Cows. Veterinary medi-cine: between from. theme. of sciences. Sat. Kharkiv, 95, 397–400 (in Ukrainian).
Sidashova, S. O. (2014). Influence of tissue preparation on normalization of sexual function of heifers. Breed-ing and genetics of animals: between from. theme. of sciences. K.: Agrarian Science, 49, 236–247 (in Ukrainian).
Sidashova, S. O., & Humeny, O. G. (2016). Influence on biotic protection of mucous membranes on the func-tion of ovaries of lactating cows. Scientific Bulletin of Veterinary Medicine, 2(130), 17–24 (in Ukrainian).
Sidashova, S. O., Avdoseva, I. K., & Grigorasheva, I. M. (2016). Probiotic protection of the mucous reproduc-tive tract and dairy productivity of cows. Scientific and Technical Bul. IBT and DNKI veterinary prod-ucts and feed additives, 16, 200–210 (in Ukrainian).
Sidashova, S., & Gumenny, O. (2017). Rhythm of sexual cycles of cows and level of the hidden early embrionic mortality. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sci-ences, 19(78), 121–128. doi: 10.15421/nvlvet7825.
Sidashova, S.O., Avdoseva, I. K., Grigorasheva, I. M. (2016). Probiotic protection of the mucous reproduc-tive tract of lactating cows. Scientific and Technical Bul. IBT and DNKI veterinary products and feed ad-ditives, 16, 199–209. (in Ukrainian).
Slivinska, L., Fedorovych, V., Gutyj, B., Lychuk, M., Shcherbatyy, A., Gudyma, T., Chernushkin, B., & Fe-dorovych, N. (2018). The occurrence of osteodystro-phy in cows with chronic micronutrients deficiency. Ukrainian Journal of Ecology, 8(2), 24–32. doi: 10.15421/2018_305.
The methodology for determining the economic efficien-cy of the use in agriculture of the results of scientific research, new technology, inventions and rationaliza-tion proposals. M.: VAIIPI, 1983, 149 p. (inRussian).
Varcholyak, I. S., & Gutyi, B. V. (2019). Determination of the chronic toxicity of preparation “Bendamin” on laboratory animals. Theoretical and Applied Veteri-nary Medicine, 7(2), 63‒68. doi: 10.32819/2019.71011.
Yong, D., Hassell, T., & Duongan, Y. (2002). Сhronic factors infections: living with unwanted guests. Nature immunology, 3(11), 1026–1032. doi: 10.1038/ni1102-1026.
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