Efficiency of complex pig therapy with pathology of the distal department of the limbs

Keywords: pigs, lameness, trifuzole, T-cells, bandage.


Studies have been conducted to establish the dynamics of the course of treatment of purulent-inflammatory process of distal limb in pigs. The treatment algorithm was presented by two schemes: classic (I – experimental screw) and experimental (II – experimental group). Among the morphological parameters investigated: hemoglobin level, erythrocyte sedimentation rate (ESR), hematocrit, leukograms, total erythrocytes and leukocytes in the blood. To determine the immunobiological activity of the body of sick pigs, serum T: lymphocytes (CD2, CD3), T-helper cells (CD4), T-suppressors/killers (CD8), IRI (T-help/T-sup.), NK cells (CD16), B-lymphocytes (CD22), immunoglobulins A, M, G, CEC and phagocytic index. Research objectives – determining the effectiveness of treatment regimens algorithm for morphological and immunological composition of the blood in different forms of lymphoma disease distal extremities in pigs. Manifestation effector function was observed a decrease in lymphocytes, proliferation and differentiation of corresponding antibodies of the immune system of pigs. Inhibition of regulatory function in the inflammatory process reduces the mechanisms of formation of biologically active compounds “chemotaxis factor”, “transfer factor”, “phagocytosis factor”, migration of neutrophils and macrophages. The decrease in the concentration of NK cells in 2 times, with the pathology open wound, indicates a decrease in the process of opsonization (antibody-dependent cellular cytotoxicity) due to the lack of immune response to pathogens in the inflammatory cell. In abscesses, purulent pododermatitis and laminitis, NK cells decrease 1.5 times with the indirect manifestation of specific cytotoxic cells (B-lymphocytes, macrophages). It is determined that the drug “Trifuzol 1%” activates effector and reparative function of specific components of immune activity (T and B lymphocytes, population of T cells, NK cells). The results of these studies in the article thoroughly show the dynamics of changes in morphological and immunological status of pigs for diseases of the musculoskeletal system of the distal extremity. The results will facilitate the work of veterinary practitioners in the treatment of nosological forms of distal limb diseases in pigs.


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Cowart, R. P., & Casteel, S. W. (2002). Muskuloskeletal diseases: foot lesions. An Outline of Swine Diseases: A Handbook, John Wiley & Sons Inc, New Jersey, 121–122.

Dewey, C. E., Straw, B. E., D’Allaire, S., Mengeling, W. L., & Taylor, D. J. (2006). Diseases of the nervous and lo-comotor systems. In: Diseases of Swine. Ames: Blackwell, 861–882.

Garcia, M. C., First, N. L., Ginther, O. J. & Rutledge, J. J. (1980). Effect of gram-negative bacterial endotoxin, oxytocin and dexamethasone on lactation in sows. Proceedings of the IPVS Congress, 67.

Harris, M. J., Pajor, E. A., Sorrells, A. D., Eicher, S. D., Richert, B. T., & Marchant-Forde, J. N. (2006). Effects of stall or small group gestation housing on the pro-duction, health and behaviour of gilts. Livestock Science, 102(1), 171–179. doi: 10.1016/j.livsci.2005.12.004.

Jensen, T. B., Bonde, M. K., Kongsted, A. G., Toft, N., & Sorensen, J. T. (2010). The interrelationships between clinical signs and their effect on involuntary culling among pregnant sows in group-housing systems. Animal, 4(11), 1922–1928. doi: 10.1017/S1751731110001102.

Karriker, L. (2013). Identifying, treating and рreventing lameness in sows. National Pork Board. Des Moines, IA USA. Retrieved from: https://porkcdn.s3. amazonaws.com/sites/all/files/documents/2013SowHousingWebinars/Lameness.pdf.

Madsen, D. (2008). A brief overview of selected disease entities diagnosed in swine. American Association of Swine Veterinarians, 2008, 3–6.

Main, D. C. J., Clegg, J., Spatz, A., & Green, L. E. (2000). Repeatability of a lameness scoring system for finishing pigs. Veterinary Record, 147, 574–576. doi: 10.1136/vr.147.20.574.

Mullan, S., Browne, W. J., Edwards, S. A., Butterworth, A., & Whay, H. R. (2009). The effect of sampling strategy on the estimated prevalence of welfare outcome measures on finishing pig farms. Applied Animal Behaviour Science, 119(1-2), 39–48. doi: 10.1016/j.applanim.2009.03.008.

Nielsen, E. O., Nielsen, N. C., & Friis, N. F. (2001). Mycoplasma hyosynoviae arthritis in grower-finisher pigs. Journal of Veterinary Medicine Series a-Physiology Pathology Clinical Medicine, 48(8), 475–486. doi: 10.1046/j.1439-0442.2001.00378.x.

Popov, K. O. (2013). Terapiya hromoty u sviney s ispol-zovaniem nesteroidnyh sredstv. Perspektivy svinivod-stva: teoriya i praktika, 3, 27–30 (in Russian).

Quinn, A., Calderon Diaz, J. A., & Boyle, L. (2013). Lameness in Pigs – Moorepark Research Dissemina-tion Day. Pig Developmen Department.

Rowles, C. (2001). Sow Lameness. Journal Swine Health Prod, 9(3), 130–131. https://www.aasv.org/shap/issues/ v9n3/v9n3p130.html.

Smith, B. (1988). Lameness in pigs associated with foot and limb disorders. In Practice, 10, 113–117. doi: 10.1136/inpract.10.3.113.

Wells, G. A. H. (1984). Locomotor disorders of the pig. In Practice, 6(2), 43–53. doi: 10.1136/inpract.6.2.43.

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Kyrychko, B., & Semirenko, V. (2020). Efficiency of complex pig therapy with pathology of the distal department of the limbs. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sciences, 22(98), 3-8. https://doi.org/10.32718/nvlvet9801