The effectiveness of “Iodozol” in combination therapy in the treatment of postpartum vulvitis in goats


  • R. M. Sachuk Rivne State University for the Humanities, Rivne, Ukraine https://orcid.org/0000-0003-4532-4220
  • Ya. S. Stravsky I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
  • O. A. Katsaraba Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, Ukraine https://orcid.org/0000-0001-8520-224X
  • C. A. Ponomareva State Scientific-Research Control Institute of Veterinary Drugs and Feed Additives, Lviv. Ukraine https://orcid.org/0000-0002-8381-1671
  • N. V. Ostapiv State Scientific-Research Control Institute of Veterinary Drugs and Feed Additives, Lviv. Ukraine https://orcid.org/0000-0002-1588-4481
  • L. V. Kalynovska State Scientific-Research Control Institute of Veterinary Drugs and Feed Additives, Lviv. Ukraine https://orcid.org/0000-0001-8992-9358
  • Ye. Ie. Kostyshyn Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies Lviv, Ukraine https://orcid.org/0000-0002-7953-8051
Keywords: goat, vulvitis, blood, efficacy, drug, “Iodozol”, “Celexib”, “Dextrodev 50”

Abstract

In the nosology of obstetric pathology of goats a special place is occupied by postpartum lesions of the genitals by pathogenic microflora, of which the lion's share are postpartum vulvitis. The aim of the study was to test a new treatment regimen for postpartum vulvitis in goats and to study the therapeutic efficacy of the drug “Iodozol”, “Celexib” and “Dextrodev 50” in this pathology. Clinical and anamnestic data showed that the symptoms of postpartum vulvitis of goats were characterized by inflammatory edema, high pain, local fever, impaired tissue integrity, hematomas and discharge from the genital tract. Microbiological studies of secretions from the genitals revealed the presence of E. coli, S. aureus, less often – S. saprophyticus and E. faecalis. High resistance of microorganisms to fluoroquinolones and penicillins is noted. E. coli was sensitive to only 35.7 % of antimicrobial drugs, including ceftriaxone, ceftiofur, and iodine. S. aureus is sensitive to 49.9 % of antimicrobial drugs, including ceftriaxone, cephalexin, gentamicin, ceftiofur, iodine (highest sensitivity) and chlorhexidine. S. saprophyticus was insensitive to a number of antibiotics (oxytetracycline, gentamicin, etc.), except iodine. Taking into account microbiological researches the complex scheme of treatment of postpartum vulvitis at goats is developed. Evaluation of the effectiveness of complex therapy of this pathology in animals showed that treatment with “Iodozole”, “Celexib” and “Dextrodev 50” in a short time eliminates inflammatory symptoms (pain, infiltration, redness, discharge). At the end of the course of treatment in the blood was observed an increase in hemoglobin concentration by 13.7 %, a decrease in the number of erythrocytes by 1.7 and leukocytes by 2.2 times compared with treatment. The topical intrauterine drug “Iodozol”, a non-steroidal injectable drug “Celexib”, has been found to have a broad spectrum of antimicrobial activity, and is effective and safe to use. The drugs have an anti-edematous and analgesic effect, and symptomatic treatment with intravenous solution “Dextrodev 50” is a mandatory component of complex therapy and is aimed at replenishing the body with nutrients, as well as helps to neutralize and remove toxins from the body. Further research will be to study the clinical efficacy and develop regulations for the use of this scheme in vulvitis and cervicitis of other ruminants.

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Abstract views: 32
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Published
2020-10-28
How to Cite
Sachuk, R., Stravsky, Y., Katsaraba, O., Ponomareva, C., Ostapiv, N., Kalynovska, L., & Kostyshyn, Y. (2020). The effectiveness of “Iodozol” in combination therapy in the treatment of postpartum vulvitis in goats. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sciences, 22(99), 193-197. https://doi.org/10.32718/nvlvet9929