Study of the properties of nanoparticles of Ag and Zn citrates
The use of nanomaterials has become especially relevant as components of new drugs, adjuvants and new ingredients in feed additives. The very combination of inorganic components (metals) with natural minerals (сeolites, clenoptolites) made it possible to create fundamentally new chemical compounds that differ significantly in the mechanism of action and their physicochemical characteristics from traditionally used drugs for the treatment of bacterial diseases of poultry. The practical application of the composition involves the use of small sizes of nanoparticles that are in the “nanoscale” from 1 to 100 nm. Our article contains the results of studies of Ag and Zn nanomaterials in combination with citrate in the form of powder and dispersed solutions. As a result of scanning electron microscopy, it was found that the studied sample of Ag and Zn nanoparticles is a gray powder of monocrystalline particles of irregular shape, the size of which varies from 160 to 350 nm. Particles of three sizes were most often found among Ag and Zn citrates, namely: 160 nm – 45 %, 210 nm – 35 %, 350 nm – 20 %. Studying the bactericidal properties of dispersed solutions of Ag and Zn citrates on microbial suspensions of test cultures of Escherichia coli (ser.O2), Salmonella typhimurium, Pseudomonas aeruginosa, Staphylococcus epidermidis, we found that Ag citrate showed better bactericidal properties in relation to all experimental test cultures of Escherichia coli (ser.O2), Salmonella typhimurium, Pseudomonas aeruginosa, Staphylococcus epidermidis, in contrast to the citrate solution Zn, which was only effective against Escherichia coli (ser.O2), and Staphylococcus epidermidis.
Fuentes-Duculan, J., Suárez-Fariñas, M., Zaba, L. A. et al. (2010). A subpopulation of CD163–positive macro-phages is classically activated in psoriasis. J. Investi-gative Dermatology, 130(10), 2412–2422. doi: 10.1038/jid.2010.165.
Hallock, M. F., Greenley, P., DiBerardinis, L., & Kallin, D. (2009). Potential risks of nanomaterials and how to safely handle materials of uncertain toxicity. Journal of Chemical Health and Safety, 16(1), 16–23. doi: 10.1016/j.jchas.2008.04.001.
Mal'ceva, P. P (2006). Mir materialov i tehnologij. Nanomaterialy. Nanotehnologii. Nanosistemnaja tehnika. M.: Tehnosfera (in Russian).
Mihajlov, G. A., & Vasil'eva, O. S (2008). Tehnologija budushhego: ispol'zovanie magnitnyh nanochastic v onkologii. Sibirskij nauchnyj medicinskij zhurnal. Bjulleten', 3, 18–22 (in Russian).
Milos, M., Mastelic, J., & Jerkovic, I. (2000). Chemical composition and antioxidant effect of glycosidically bound volatile compounds from oregano. Food Chemistry, 71(1), 79–83. doi: 10.1016/S0308-8146(00)00144-8.
Orishchuk, O. S., Tsap, S. V., Chernenko, O. M., Darmograi, L. M., Chernenko, O. I., & Mykytiuk, V. V. (2019). Environmental justification for using of active yeast in laying hens diet. Ukrainian Journal of Ecology, 9(2),189–194. URL: https://www.ujecology.com/articles/ environmental-justification-for-using-of-active-yeast-in-laying-hens-diet.pdf.
Salmon, I., & Hrytsyna, M. (2019). Veterynarna medytsyna i vykorystannia likarskykh roslyn. Nau-kovyi visnyk LNU veterynarnoi medytsyny ta biotekhnolohii imeni S. Z. Gzhytskoho. Seriia: Veterynarni nauky, 21(94), 121–126. doi: 10.32718/nvlvet9422 (in Ukrainian).
Trakhtenberh, I. M., & Dmytrukha, N. M. (2013). Nanochastynky metaliv, fizyko–khimichni ta toksychni vlastyvosti. Ukrainskyi zhurnal z problem medytsyny pratsi, 4(37), 62–74. URL: http://nbuv.gov.ua/UJRN/ Ujpmp_2013_4_8 (in Ukrainian).
Warheit, D., Webb, T., Colvin, V., Reed, K., & Sayes, C. (2007). Pulmonary bioassay studies with nanoscale and fine-quartz particles in rats: toxicity is not dependent upon particle size but on surface characteristics. Toxicol. Sci., 95(1), 270–280. doi: 10.1093/toxsci/kfl128.
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