Pathomorphology of cat pancreas under chronic pancreatitis


Keywords: morphology, microscopic structure, pancreas, morphological parameters, swelling, acini, necrosis, stagna-tion, focuses of haemorrhages, hyalinosis.

Abstract

The paper deals with studying the pathomorphology of cat pancreas under chronic pancreatitis. This paper is a component of a research mix of the Department of Anatomy and Histology, it goes under the title “The development, morphology and histo-chemistry of animal organs in health and in disease”, (state registration number № 0120U100796). A pancreas is an azygos parenchymatous organ which refers to the endoexocrine glands, includes exocrine and endocrine pancreas, is involved in the processes of digestion and regulation of carbohydrate metabolism, protein metabolism and lipid exchange in tissues. Pancreatic juice, which is rich in enzymes (trypsin, lipase, amylase), is produced in an exocrine pancreas, and hormones (insulin, somatostatin, glucagon (vasoactive intestinal polypeptide), pancreatic polypeptide) are produced in endocrine pancreas. This galand is involved in the process of digestion while producing digestive enzymes, which get into the duodenum and hydrolyze practically all parts of feeds which enter the body. It is located in an abdominal cavity, anatomically connected with a stomach, liver and duedenum. It has been found that pathomorphological changes in pancreas under chronic pancreatits manifest themselves depending on the disease stage and are revealed by insignificant progress of the pathological process. Herewith, morphological parameters of pancreas width and length in cats under chronical pancreatitis did not significantly change, but these indices tended to decrease. Its absolute weight  in cats under chronical pancreatitis, as compared with clinically healthy cats, did not change and equalled 9.12 ± 2.03 g. But pancreas relative weight in sick cats increased by 1.4 (Р 0.01) and equalled 0.51 ± 0.08 %, as compared with control 0.38 ± 0.06 %. Under histological analysis of pancreas histology specimen stained with hematoxylin Corazzi and eosin, some distortion in a microscopic structure of a pancreas was observed, it manifested itself in thickening of interparticle tissue-connective layers which spread like desmogenous bands. Some destructive changes in acini in exocrinal pancreas, which manifested themselves in losing their characteristic form, were noticed. The cytoplasm of such acinous cells was in a state of plasmorrhexis, the pycnosis was observed.

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Published
2021-06-19
How to Cite
Kovalchuk, O., Goralskyi, L., & Sokulskyi, I. (2021). Pathomorphology of cat pancreas under chronic pancreatitis. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sciences, 23(102), 87-92. https://doi.org/10.32718/nvlvet10213