IMMUNOLOGICAL BLOOD PARAMETERS OF CALVES WITH THE USE OF ARSELAN


  • T. Ignatieva Kharkiv State Veterinary Academy, Kharkiv
  • V Liasota Bilotserkivskiy National Agrarian University, Bila Tserkva
  • V. Popsuy Sumy National Agrarian University, Sumy
Keywords: calves, immunological parameters, T- and B-lymphocytes, immunostimulant arselan, survival

Abstract

Objective of this work is to examine the features of formation of nonspecific resistance using fully integrated arselan immunostimulant comprising: selenite, sodium selenite, potassium, interferon, silver nanoparticles, nanoparticles of iron, copper nanoparticles, retinol acetate, cholecalciferol, α-tocopherol acetate. The studies were performed on calves of a black-motley breed. The drug was injected intramuscularly at a dose of 2 ml / head 2-5 and 14 days after birth. During the experiment the hygienic conditions of the calves, their survival and growth rate were taken into account. In order to assess the immune status of the organism, T- and B-lymphocytes in peripheral blood were determined. It was found that parenteral use of immunostimulatory drugs contributed to activation of antigen specific immunity of animals, such as increase of immune cells functional activity: accelerates the proliferation, differentiation of T-lymphocytes by 26.6 %, increases the activity of T-cells by 19.6 % and theophylline resistant ones by 32 %, increases the number of B-lymphocytes by 8.1%, the activity of plasma membrane receptor system by 12%. The above mentioned biological drug contributed to intensive growth of live body weight by 12–15 %, additional growth by 1.8–2 kg and survival of 90-100% of animals.


Downloads

Download data is not yet available.

Author Biographies

T. Ignatieva, Kharkiv State Veterinary Academy, Kharkiv
PhD student
V Liasota, Bilotserkivskiy National Agrarian University, Bila Tserkva
Doctor of Veterinary Science, Professor
V. Popsuy, Sumy National Agrarian University, Sumy
Candidate of Agricultural Sciences, Associate Professor

References

Antonenko, P. P. Novyj preparat dlja korekcii' imunnoi' systemy u molodnjaka sil's'kogospodars'kyh tvaryn / P. P. Antonenko, O. S. Rybalko, O. L. Jelesjejev ta in. Visnyk Poltavs'koi' derzhavnoi' agrarnoi' akademii'. – 2003. – № 1. – S. 25–26. (in Ukrainian).

Bjem, Je. Prostaja radial'naja immunodisfuzija po Manchini / Je. Bjem // Immunologicheskie metody. – M. 1987. – S. 49–57. (in Russian).

Volkov, G. K. Gigiena vyrashhivanija zdorovogo molodnjaka / G. K. Volkov // Veterinarija. – 2003. – № 1. – S. 3–6. (in Russian).

Karput', I. M. Zakonomernosti formirovanija immunnogo statusa i razvitija immunnoj nedostatochnosti u zhivotnyh / I. M. Karput' // Agrar. nauka na rubezhe HH1 v. – Minsk, 2000. – S. 228–230. (in Russian).

Kvachov, V. G., Ushkalov V. O., Roman'ko M. Je. Vzajemodija z imunnoju systemoju jak kryterij ocinky i vidboru imunobiologichnyh preparativ / V. G. Kvachov, V. O. Ushkalov, M.Je. Roman'ko // Veterynarna biotehnologija. – Kyi'v.: Tryada Pljus, 2009. – B. № 14. – S. 19–24. (in Ukrainian).

Pathak, D. Flavoidsas medicinal agents resents ad-vances / D. Pathak, K. Pathak, A. Singla // Fitoterapia. – 1991. – № 62. – № 5. – P. 371–389.

Samburov, N. V. Fiziologicheskie i immunologicheskie aspekty primenenija immunostimuljatorov / N. V. Samburov // Doklady RASHN. – 2006. –№1.– S. 41–43. (in Russian).

Samburov, N. V. Vlijanie jenergometabolicheskogo sostava na morfologicheskie i biohimicheskie pokazateli krovi teljat / N. V. Samburov, A. A. Toldykina, I. L. Palaus // Molodoj uchenyj. – Kazan' 2015 № 8. – S. 49–52. (in Russian).

Chornyj, M. V. Praktykum z gigijeny tvaryn / M. V. Chornyj, O. P. Prokudin, O. S. Vovk. – HHZVA.–1994.–104 s. (in Ukrainian).

Chornyj, M. V. Sanitarno-gigijenichne zabezpechennja rezystentnosti teljat pry vykorystanni probiotykiv i antyoksydantiv / M. V. Chornyj, I. V. Garkusha // VMUK.-2015. – № 2.–S. 30–33. (in Ukrainian).

Chumachenko, V. Imunologichnyj kontrol' preparativ – vymoga chasu // Veterynarna medycyna Ukrai'ny. – 2003. – № 1. – S. 19. (in Ukrainian).

Abstract views: 64
PDF Downloads: 55
Published
2015-03-17
How to Cite
Ignatieva, T., Liasota, V., & Popsuy, V. (2015). IMMUNOLOGICAL BLOOD PARAMETERS OF CALVES WITH THE USE OF ARSELAN. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sciences, 17(3), 43-48. Retrieved from https://nvlvet.com.ua/index.php/journal/article/view/516
Section
Physiological-biochemical and biotechnological ways of animal productivity increasing