COMPARATIVE EFFECTIVENESS THERAPEUTIC AND PROPHYLACTIC PREPARATIONS WHEN APPLYING 3% OF ETHANOL–WATER EMULSION OF PROPOLIS AND ANTIBIOTICS FOR CATARRHAL PNEUMONIA IN CALVES
Catarrhal bronchopneumonia of calves appears on the background of adverse environmental factors, actions conditionally pathogenic microflora particularly Str.pneumoniae and their associations that cause immune deficiency of animals. Experimental research was carried out in the agricultural firm Ltd. «Pravda» Brody district, Lviv region. For research it was formed three groups of calves: first – control (healthy calves 5 goals); second and third groups – research (calves suffering from catarrhal bronchopneumonia caused by the causative agent Str. pneumoniae – 7 goals), as well as the a third research group – 7 goals, diseases caused by microorganisms association (isolated from nasal exudate).
Pseudomonas aeruginosa, Staphylococcus epidermidis, Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli. were isolated from the nasal passages of calves on catarrhal bronchopneumonia.
Materials of antibiotic gramme showed the highest sensitivity cultures of bacteria isolated from nasal fluid holes of calves suffering from catarrhal bronchopneumonia to 3% of ethanol–water emulsion of propolis.
The use of aerosols to 3% of ethanol–water emulsion of propolis with medicinal purposes for catarrhal bronchopneumonia of calves, 1 time a day, during 6 days contributed the stimulation of cellular and humoral factors of calves body protection and their recovery. After use of aerosols – 3% of ethanol–water emulsion of propolis in calves suffering from catarrhal bronchopneumonia, of both research groups in serum was increased the content: in calves of the first group Ig G to 8.18 mg/ml, Ig M to 0.7 mg/ml, and second, respectively, 6.85 mg/ml and 0.3 mg/ml.
It was noted a level decrease of CIC 1.6 times compared with the data of sick animals. The use of 3% alcohol–water emulsion of propolis to the calves with catarrhal bronchopneumonia contributed to increased activity of bactericidal and lizocimic activity whereby these figures were higher in the first experimental group of calves, in which Str. pneumoniae was the causative agent, compared with calves from the second research group. Prophylactic use of aerosols of 3% ethanol – water emulsion of propolis prevented disease in calves with catarrhal bronchopneumonia.
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