INFLUENCE OF COMPLEX TREATMENT OF CALVES SUFFERING FROM HIPOPLASTIC ANEMIA FOR METABOLISM OF METALLOPROTEINS AND ENZYME ACTIVITY OF ANTIOXIDANT DEFENSE SYSTEM
The research results of calves suffering from hypo plastic anemia of iron content, enzyme activity of antioxidant protection (AOP) and the exchange metal protein are listed in the paper.
Trace element ration adjustments of calves were performed by including premixes scarce trace elements, which were in the form of sulphates ME (the first experimental group) and methionine chelate compounds (the second experimental group).
It is established that the complex treatment of calves eliminates the major clinical symptoms of iron deficiency, normalizes metal enzyme activity of various components of the system AOP. In particular at the end of the experiment, the concentration of iron significantly (p < 0,001) was increased at 1.9 and 2.2 times, the haptoglobin level of was respectively higher at 47.1% and 49.3% compared to the beginning of the experiment.
The malonic dialdehyde concentration in serum of calves of the first group decreased by 20.3% (p < 0.001) in the second group, where chelate compounds were applied – by 29.8% (p <0.001).
As a result of the treatment the hemoenzyme activity increased: catalases by 31.2% and 36,8% (p < 0,001), peroxidase by 37,6% (p < 0.01) and 49.2% (p < 0.001) and cytochrome oxidase by 54.7% (p <0.01) and 86.5% (p < 0.001).
Determination of investigated metal protein can be informative diagnostic criteria for metabolic disorders of calves suffering from hypo plastic anemia. The best therapeutic effect in the treatment of calves of the second group is made, which got minerals in the form of chelate compounds.
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