TY - JOUR AU - S. Sidashova AU - B. Gutyj AU - V. Khalak AU - O. Humeny PY - 2020/05/07 Y2 - 2024/03/29 TI - Influence of complex action of probiotic and specific prophylaxis of associated mucosal diseases on some quantitative traits of dairy cattle performance JF - Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sciences JA - nvlvet VL - 22 IS - 97 SE - Articles DO - 10.32718/nvlvet9714 UR - https://nvlvet.com.ua/index.php/journal/article/view/3899 AB - The article presents the results of studies of indicators of reaching the age of the first calving of repair heifers of the Ukrainian red dairy breed under the conditions of use of the complex scheme of specific immunoprophylaxis and preparation “Multibacterin veterinary suspension”.The research was conducted in the conditions of the industrial complex for milk production of Dolinskoye LLC, Odessa region. The subjects of the study were groups-analogues of breeding heifers and the firstborn of the genotype.The assessment of repair young growth indicators was performed taking into account the following indicators: age of fertile insemination, months; age of first calving, months; milk production for 100 and 305 days of the first lactation, kg. For the functional evaluation of the digestive status of animals used to determine the transit of feed, in % and the assessment of acid-base status of faeces, pH unit. The following indicators were investigated in the serum of repair calves of mating age: total protein, g/l; albumin, g/l; globulin, g/l; glucose, mmol/l; urea, mmol/l; alkaline phosphatase, units/l and liver enzymes (ALT and AST, units/l).The economic efficiency of the results of the studies was calculated according to the indicator “average hope of one cow for 305 days of the first lactation, kg”. It was found that, due to the positive simultaneous effect of probiotic protection of the intestinal mucous membranes, repair heifers showed a higher growth and development rate and the first calving had 28.07 months, which is 2.31 months (8.45 %) earlier than in control (P < 0.001).The optimization of the technology of growing heifers for the use in the scheme of specific immunoprophylaxis of a probiotic drug – immunomodulator, which feed use had a prolonged positive effect not only on the growth parameters of young animals, but also on the increase of milk productivity per first lactation was experimentally proved.Calculations of cost-effectiveness of research results showed that the maximum increase in production (+ 9.10 %) was obtained from the firstborn of the experimental group born to cows mothers older than two lactations, where the scheme of specific prevention of associated diseases was carried out for repair heifers with previous normophilic laceration probiotic feed preparation. ER -